Agent Name

Aminocarb

CAS Number

2032-59-9

Formula

C11-H16-N2-O2

Major Category

Pesticides

Synonyms

(4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamaat [Dutch]; (4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamat [German]; (4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamate; (4-Dimetilamino-3-metil-fenil)-N-metil-carbammato [Italian]; 3-Methyl-4-dimethylaminophenyl methylcarbamate; 4-(Dimethylamino)-3-methylphenol methyl carbamate (ester); 4-(Dimethylamino)-3-methylphenol methylcarbamate (ester); 4-(Dimethylamino)-3-methylphenyl methylcarbamate; 4-(Dimethylamino)-m-tolyl methylcarbamate; 4-Dimethylamine m-cresyl methylcarbamate; 4-Dimethylamine-m-cresyl methylcarbamate; 4-Dimethylamino-3-cresyl methylcarbamate; A 363; Aminocarbe [ISO-French]; BAY 44646; Bayer 44646; Bayer 5080; Carbamic acid, methyl-, 4-(dimethylamino)-3-methylphenyl ester; Carbamic acid, methyl-, 4-(dimethylamino)-m-tolyl ester; Matacil; Matacil 180D; Methylcarbamic acid 4-(dimethylamino)-m-tolyl ester; Mitacil; N-N-Methylcarbamate de 4-dimethylamino 3-methyl phenyle [French]; Phenol, 4-(dimethylamino)-3-methyl-, methylcarbamate (ester); m-Cresol, 4-(dimethylamino)-, methylcarbamate (ester); [ChemIDplus] UN2757

Category

Carbamate Insecticides

Description

White solid; [ICSC] Colorless solid; [MSDSonline]

Sources/Uses

Used as insecticide for control of forest pests and chewing insects in cotton and field crops; Discontinued in 1989 by Bayer AG; [HSDB]

Comments

A cholinesterase inhibitor that may have nervous system effects causing convulsions and respiratory failure; Can be absorbed through skin; May also cause long term effects to nervous system and liver; [ICSC] No significant adverse effects in rats fed 200 mg/kg diet for 2 years; [HSDB] No inhibition of brain cholinesterase activity or histopathological tissue changes observed in feeding studies with rats; In a three generation study with rats a decrease in litter size and mean pup weight was observed, but no adverse morphological tissue changes; Changes to liver observed in long term studies with rats and dogs; No evidence of delayed neurotoxicity in hens; Mortality from lethal doses usually occurred within half hour; Sub-lethal dosing recovery often within three hours; [Reference #1] See "CARBAMATE INSECTICIDES."

Restricted

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Reference Link

INCHEM JMPR: Aminocarb - 1979

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

1.88E-6 mm Hg

Lethal Concentration

LD50 (rat) = 200 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Carbamate pesticide, solid, toxic."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Carbamate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: