Agent Name

Aminocarb

CAS Number

2032-59-9

Formula

C11-H16-N2-O2

Major Category

Pesticides

Synonyms

(4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamaat [Dutch]; (4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamat [German]; (4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamate; (4-Dimetilamino-3-metil-fenil)-N-metil-carbammato [Italian]; 3-Methyl-4-dimethylaminophenyl methylcarbamate; 4-(Dimethylamino)-3-methylphenol methyl carbamate (ester); 4-(Dimethylamino)-3-methylphenol methylcarbamate (ester); 4-(Dimethylamino)-3-methylphenyl methylcarbamate; 4-(Dimethylamino)-m-tolyl methylcarbamate; 4-Dimethylamine m-cresyl methylcarbamate; 4-Dimethylamine-m-cresyl methylcarbamate; 4-Dimethylamino-3-cresyl methylcarbamate; A 363; Aminocarbe [ISO-French]; BAY 44646; Bayer 44646; Bayer 5080; Carbamic acid, methyl-, 4-(dimethylamino)-3-methylphenyl ester; Carbamic acid, methyl-, 4-(dimethylamino)-m-tolyl ester; Matacil; Matacil 180D; Methylcarbamic acid 4-(dimethylamino)-m-tolyl ester; Mitacil; N-N-Methylcarbamate de 4-dimethylamino 3-methyl phenyle [French]; Phenol, 4-(dimethylamino)-3-methyl-, methylcarbamate (ester); m-Cresol, 4-(dimethylamino)-, methylcarbamate (ester); [ChemIDplus] UN2757

Category

Carbamate Insecticides

Description

White solid; [ICSC] Colorless solid; [MSDSonline]

Sources/Uses

Used as insecticide for control of forest pests and chewing insects in cotton and field crops; Discontinued in 1989 by Bayer AG; [HSDB]

Comments

A cholinesterase inhibitor that may have nervous system effects causing convulsions and respiratory failure; Can be absorbed through skin; May also cause long term effects to nervous system and liver; [ICSC] No significant adverse effects in rats fed 200 mg/kg diet for 2 years; [HSDB] No inhibition of brain cholinesterase activity or histopathological tissue changes observed in feeding studies with rats; In a three generation study with rats a decrease in litter size and mean pup weight was observed, but no adverse morphological tissue changes; Changes to liver observed in long term studies with rats and dogs; No evidence of delayed neurotoxicity in hens; Mortality from lethal doses usually occurred within half hour; Sub-lethal dosing recovery often within three hours; [Reference #1] See $CARBAMATE INSECTICIDES.$

Restricted

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Reference Link

INCHEM JMPR: Aminocarb - 1979

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

1.88E-6 mm Hg

Lethal Concentration

LD50 (rat) = 200 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for $Carbamate pesticide, solid, toxic.$

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Carbamate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: