| Agent Name | Chromyl chloride |
|---|---|
| Alternative Name | Chromium oxychloride |
| CAS Number | 14977-61-8 |
| Formula | Cl2-Cr-O2 |
| Major Category | Metals |
| Synonyms | Chlorochromic anhydride; Chlorure de chromyle [French]; Chromic oxychloride; Chromium (VI) dioxychloride; Chromium chloride oxide; Chromium chloride oxide (CrO2Cl2); Chromium dichloride dioxide; Chromium dioxide dichloride; Chromium oxychloride (CrO2Cl2); Chromium(VI) dioxychloride; Chromium, dichlorodioxo-; Chromoxychlorid [German]; Chromyl chloride (CrO2Cl2); Chromylchlorid [German]; Chroomoxychloride [Dutch]; Cromile, cloruro di [Italian]; Cromo, ossicloruro di [Italian]; Dichlorodioxochromium; Dioxodichlorochromium; Oxychlorure chromique [French]; [ChemIDplus] UN1758 |
| Category | Chromium Compounds, Inorganic |
| Description | Deep-red liquid with a musty, burning, acrid odor; Note: Fumes in moist air; [NIOSH] "Opaque, dark, blood-red liquid at room temp."; Reacts vigorously in water at 20 deg C to form Cr(VI) trioxide (sparingly soluble in water), HCL, and Cl2; [ACGIH] |
| Sources/Uses | Used in organic synthesis, as a solvent for CrO3, and as a catalyst; [ACGIH] |
| Comments | Liquid causes second or third degree burns after short contact; [CHRIS] Releases large amounts of HCl when spilled in water; [ERG 2016] No animal or human data available, but treated as a water soluble form of hexavalent chromium; Insufficient data for carcinogenicity notation; [ACGIH] A corrosive substance that can cause pulmonary edema after inhalation of vapor; [ICSC] Chronic exposure to hexavalent chromium may produce evidence of kidney and liver injury. [ATSDR Case Studies # 4] See "Chromium" and linked occupational diseases. |
| Exposure Assessment | |
| Skin Designation (ACGIH) | Yes |
| TIH | Yes |
| Dangerous When Wet | Yes - A material that, by contact with water, is liable to become spontaneously flammable or to give off flammable or toxic gas at a rate greater than 1 L per kilogram of the material, per hour; [ERG 2004] |
| Bioaccumulates | Yes |
| TLV (ACGIH) | 0.0001 ppm, as Cr(VI), inhalable fraction and vapor |
| STEL (ACGIH) | 0.00025 ppm, as Cr(VI), inhalable fraction and vapor |
| Vapor Pressure | 20 mm Hg |
| Explanatory Notes | Not TIH in land-based spills, but TiH substance released when spilled in water; [ERG 2016] |
| Reference Link | |
| Adverse Effects | |
| Skin Sensitizer | Yes |
| Asthma | Yes |
| Toxic Pneumonitis | Yes |
| Hepatotoxin | Hepatotoxin, Secondary |
| Nephrotoxin | Yes |
| Dermatotoxin | Skin Burns |
| IARC Carcinogen | Known Carcinogen |
| NTP Carcinogen | Human Carcinogen |
| ACGIH Carcinogen | Confirmed Human |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Diseases | Occupational diseases associated with exposure to this agent: |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
Chromyl chloride
Alternative Name
Chromium oxychloride
CAS Number
14977-61-8
Formula
Cl2-Cr-O2
Major Category
Metals
Synonyms
Chlorochromic anhydride; Chlorure de chromyle [French]; Chromic oxychloride; Chromium (VI) dioxychloride; Chromium chloride oxide; Chromium chloride oxide (CrO2Cl2); Chromium dichloride dioxide; Chromium dioxide dichloride; Chromium oxychloride (CrO2Cl2); Chromium(VI) dioxychloride; Chromium, dichlorodioxo-; Chromoxychlorid [German]; Chromyl chloride (CrO2Cl2); Chromylchlorid [German]; Chroomoxychloride [Dutch]; Cromile, cloruro di [Italian]; Cromo, ossicloruro di [Italian]; Dichlorodioxochromium; Dioxodichlorochromium; Oxychlorure chromique [French]; [ChemIDplus] UN1758
Category
Chromium Compounds, Inorganic
Description
Deep-red liquid with a musty, burning, acrid odor; Note: Fumes in moist air; [NIOSH] "Opaque, dark, blood-red liquid at room temp."; Reacts vigorously in water at 20 deg C to form Cr(VI) trioxide (sparingly soluble in water), HCL, and Cl2; [ACGIH]
Sources/Uses
Used in organic synthesis, as a solvent for CrO3, and as a catalyst; [ACGIH]
Comments
Liquid causes second or third degree burns after short contact; [CHRIS] Releases large amounts of HCl when spilled in water; [ERG 2016] No animal or human data available, but treated as a water soluble form of hexavalent chromium; Insufficient data for carcinogenicity notation; [ACGIH] A corrosive substance that can cause pulmonary edema after inhalation of vapor; [ICSC] Chronic exposure to hexavalent chromium may produce evidence of kidney and liver injury. [ATSDR Case Studies # 4] See "Chromium" and linked occupational diseases.
Exposure Assessment
Skin Designation (ACGIH)
Yes
TIH
Yes
Dangerous When Wet
Yes - A material that, by contact with water, is liable to become spontaneously flammable or to give off flammable or toxic gas at a rate greater than 1 L per kilogram of the material, per hour; [ERG 2004]
Bioaccumulates
Yes
TLV (ACGIH)
0.0001 ppm, as Cr(VI), inhalable fraction and vapor
STEL (ACGIH)
0.00025 ppm, as Cr(VI), inhalable fraction and vapor
Vapor Pressure
20 mm Hg
Explanatory Notes
Not TIH in land-based spills, but TiH substance released when spilled in water; [ERG 2016]
Reference Link
Adverse Effects
Skin Sensitizer
Yes
Asthma
Yes
Toxic Pneumonitis
Yes
Hepatotoxin
Hepatotoxin, Secondary
Nephrotoxin
Yes
Dermatotoxin
Skin Burns
IARC Carcinogen
Known Carcinogen
NTP Carcinogen
Human Carcinogen
ACGIH Carcinogen
Confirmed Human
Links to Other NLM Databases
Toxicity Information
Chemical Information
Related Information in HazMap
Diseases
Occupational diseases associated with exposure to this agent: