Agent Name

Chromyl chloride

Alternative Name

Chromium oxychloride

CAS Number

14977-61-8

Formula

Cl2-Cr-O2

Major Category

Metals

Synonyms

Chlorochromic anhydride; Chlorure de chromyle [French]; Chromic oxychloride; Chromium (VI) dioxychloride; Chromium chloride oxide; Chromium chloride oxide (CrO2Cl2); Chromium dichloride dioxide; Chromium dioxide dichloride; Chromium oxychloride (CrO2Cl2); Chromium(VI) dioxychloride; Chromium, dichlorodioxo-; Chromoxychlorid [German]; Chromyl chloride (CrO2Cl2); Chromylchlorid [German]; Chroomoxychloride [Dutch]; Cromile, cloruro di [Italian]; Cromo, ossicloruro di [Italian]; Dichlorodioxochromium; Dioxodichlorochromium; Oxychlorure chromique [French]; [ChemIDplus] UN1758

Category

Chromium Compounds, Inorganic

Description

Deep-red liquid with a musty, burning, acrid odor; Note: Fumes in moist air; [NIOSH]

Sources/Uses

Used in organic synthesis, as a solvent for CrO3, and as a catalyst; [ACGIH]

Comments

Liquid causes second or third degree burns after short contact; [CHRIS] Releases large amounts of HCl when spilled in water; [ERG 2012] No animal or human data available, but treated as a water soluble form of hexavalent chromium; Insufficient data for carcinogenicity notation; [ACGIH] A corrosive substance that can cause pulmonary edema after inhalation of vapor; [ICSC] Chronic exposure to hexavalent chromium may produce evidence of kidney and liver injury. [ATSDR Case Studies # 4] See "Chromium" and linked occupational diseases.

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TIH

Yes

Dangerous When Wet

Yes - A material that, by contact with water, is liable to become spontaneously flammable or to give off flammable or toxic gas at a rate greater than 1 L per kilogram of the material, per hour; [ERG 2004]

Bioaccumulates

Yes

TLV (ACGIH)

0.02 ppm, as Cr

Vapor Pressure

20 mm Hg

Explanatory Notes

See "2017 Notice of Intended Changes." [TLVs and BEIs]

Reference Link

ICSC: Chromyl chloride

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: