Agent Name

Clopidol

Alternative Name

Coyden

CAS Number

2971-90-6

Formula

C7-H7-Cl2-N-O

Major Category

Other Uses

Synonyms

2,6-Dimethyl-3,5-dichloro-4-pyridinol; 3,5-Dichloro-2,6-dimethyl-4-pyridinol; 3,5-Dichloro-4-hydroxy-2,6-dimethylpyridine; Clopidolo [DCIT]; Clopidolum [INN-Latin]; Coccidiostat C; Coyden; Coyden 25; Lerbek; Methylchloropindol; Methylchlorpindol; Metichlorpindol; Meticlorpindol; Rigekokcin (rigecoccin); 4-Pyridinol, 3,5-dichloro-2,6-dimethyl-; [ChemIDplus]

Category

Animal Feed Additives

Description

White to light-brown, crystalline solid; [NIOSH]

Sources/Uses

A coccidiostat used in veterinary medicine; [Merck Index] Dorland's Illustrated Medical Dictionary defines a coccidiostat as, "any of a group of chemical agents, e.g., nitrofurazone, nitrophenide, nicarbazin, mixed in feed or drinking water to control coccidiosis in animals."

Comments

Low acute oral toxicity; Absence of adverse effects in chronic studies at 5-15 mg/kg; A mild eye irritant; TLV Basis: Mutagenic effect; [ACGIH] Allergic contact dermatitis reported in feed mill workers; [Kanerva, p. 1772]

Reference Link

Occupational dermatitis in animal feed mill workers

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

3 mg/m3, inhalable fraction and vapor

PEL (OSHA)

15 mg/m3(total dust), 5 mg/m3(respirable fraction)

Adverse Effects
Skin Sensitizer

Yes

Reproductive Toxin

Yes

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: