Agent Name

Anisole

CAS Number

100-66-3

Formula

C7-H8-O

Major Category

Other Classes

Synonyms

Anizol; Benzene, methoxy; Ether, methyl phenyl; Methoxybenzene; Methyl phenyl ether; Phenoxymethane; Phenyl methyl ether; [ChemIDplus] UN2222

Category

Ethers, Other

Description

Colorless to yellow liquid; [ICSC] Clear colorless liquid; Insoluble in water; [MSDSonline] Spicy, sweet odor; [Ullmann]

Sources/Uses

Used as a vermicide, flavoring agent, solvent, and heat transfer medium; Used in the production of fragrances, pharmaceuticals, and other organic compounds; [HSDB]

Comments

Causes CNS depression in high-dose animal studies; [HSDB] A skin, eye, and respiratory tract irritant; [ICSC] May cause irritation; [MSDSonline]

Exposure Assessment
Vapor Pressure

3.54 mm Hg

Lethal Concentration

LC50 (rat) > 5,000 mg/m3

Explanatory Notes

Flash point = 52 deg C; [HSDB]

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: