Agent Name

Apholate

CAS Number

52-46-0

Formula

C12-H24-N9-P3

Major Category

Pesticides

Synonyms

1,3,5,2,4,6-Triazatriphosphorine, 2,2,4,4,6,6-hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-; 1-Aziridinylphosphonitrile trimer; 2,2,4,4,6,6-Hexahydro-2,2,4,4,6,6-hexakis(1-aziridinyl)-1,3,5,2,4,6-triazatriphosphorine; 2,2,4,4,6,6-Hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-1,3,5,2,4,6-triazatriphosphorine; 2,2,4,4,6,6-Hexakis(1-aziridinyl)cyclotriphosphaza-1,3,5-triene; APN; Afolat [Czech]; Aziridine, 1,3,5,2,4,6-triazatriphosphorine derivative; CB 40068; Hexa(1-aziridinyl)-1,3,5-phosphotriazine; Hexa(1-aziridinyl)triphosphotriazine; Hexakis (1-aziridinyl)phosphonitrilate; Hexakis(aziridinyl)phosphotriazine; Hexakis-(1-aziridinyl)phosphonitrile; Myko 63; Olin MO. 2174; PN6; Pholate; SQ 8388; [ChemIDplus]

Category

Other Insecticides

Description

Solid; [Merck Index]

Sources/Uses

Used as an insect chemosterilant (prevents reproduction in certain insects); [HSDB]

Comments

In high-dose animal studies, causes hepatitis and kidney injury; Causes ataxia and paralysis in birds; [RTECS] Mechanism appears to be as alkylating agent on genetic material; Causes marked leukopenia in mammals within 24 hours of injection; Mutagenic in Neurospora crassa; [HSDB]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

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Processes

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