Agent Name

Aspon

CAS Number

3244-90-4

Formula

C12-H28-O5-P2-S2

Major Category

Pesticides

Synonyms

A 42; A 42 (VAN); ASP 51; Bis(O,O-di(n-propyl))phosphorothionic anhydride; Bis-O,O-di-n-propylphosphorothionic anhydride; E 8573; NPD; O,O,O,O-Tetra-n-propyl dithiopyrophosphate; O,O,O,O-Tetrapropyl dithiopyrophosphate; Propyl thiopyrophosphate; Propyl thiopyrophosphate (((PrO)2P(S))2O); Stauffer ASP-51; Tetra-n-propyl dithionopyrophosphate; Tetra-n-propyl dithiopyrophosphate; Tetrapropyl dithiopyrophosphate; Tetrapropyl thiodiphosphate; Tetrapropyl thiopyrophosphate (8CI); Tetrapropyldithiodifosfat [Czech]; Thiodiphosphoric acid (((HO)2P(S))2O), tetrapropyl ester; Thiodiphosphoric acid tetrapropyl ester (9CI); Thiopyrophosphoric acid (((HO)2PS)2O), tetrapropyl ester; Thiopyrophosphoric acid, tetrapropyl ester; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Straw to amber-colored liquid; [HSDB] Amber liquid; [MSDSonline]

Sources/Uses

Used as insecticide and acaricide to protect lawns and turf; [HSDB]

Comments

Depressed cholinesterase activity in 90-day feeding study of rats at doses below lethal levels; Showed no evidence of mutagenicity; [HSDB] Effects in high-dose animal studies include convulsions and inhibition of true cholinesterase; [RTECS] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

1.07E-5 mm Hg

Explanatory Notes

Flash point = 149 deg C; [HSDB]

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: