Agent Name

Cresol, all isomers

CAS Number

1319-77-3; 95-48-7; 106-44-5; 108-39-4

Formula

C7-H8-O

Major Category

Other Classes

Synonyms

Crysylol; Tricresol; Cresol (All Isomers); Cresylic acid; Cresol (mixed isomers); Mixed cresols; m-,p-cresol mixture; Hydroxytoluene; Coal tar acids; Coal tar cresols; Coal tar phenols;[ChemFinder]

Category

Phenols

Description

Colorless or yellow crystals or liquid with a sweet tarry odor; [NIOSH]

Sources/Uses

Used as an ore flotation agent, disinfectant, and fumigant; an intermediate for chemicals, resins, dyes, photographic developers, explosives, etc.; [ACGIH] Used in degreasing, disinfecting, and photo developing; [HSDB]

Comments

Liquid or crystals cause second degree burns after contact for a few minutes; [CHRIS]; Corrosive to skin; [Quick CPC] Eye contact with concentrated solutions causes permanent corneal opacification. A drop of a 33% solution applied to rabbits eyes and removed by irrigation within 1 minute causes only temporary, moderate injury. [ACGIH] Liver injury and methemoglobinemia have been reported after suicidal ingestions. [HSDB]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

20 mg/m3, inhalable fraction and vapor

PEL (OSHA)

22 mg/m3

IDLH (NIOSH)

1108 mg/m3

Excerpts from Documentation for IDLHs

Other animal data: Rats exposed to a saturated concentration of cresol vapors (about 150 to 380 ppm) survived the exposure for 8 hours [Smyth 1956]. Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

0.17 mm Hg

Odor Threshold Low

5.0E-5 mg/m3

Odor Threshold High

0.0079 mg/m3

Explanatory Notes

Detection odor threshold for m-cresol from AIHA (mean = 0.0006 ppm);

Half Life

Within 1-2 days; [TDR, p. 412]

Reference Link

ATSDR - ToxFAQs - Cresols

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: