Agent Name

Azadirachtin

CAS Number

11141-17-6

Formula

C35-H44-O16

Major Category

Pesticides

Synonyms

Azadirachtin A; Azadirachtin-A; Bioneem; NeemAzal; [ChemIDplus]

Category

Other Insecticides

Description

Yellow-green solid; [HSDB]

Sources/Uses

A tetranortriterpinoid isolated from different plants; Insect feeding deterrent; [Merck Index] Used as an insecticide; Registered for use in the US; [HSDB] Derived from the neem tree indigenous to India and Burma; Also has nematicidal and antifungal effects; [Krieger, p. 147]

Comments

Toxic by ingestion--causes seizures and coma; [HSDB] Commercial neem formulations may contain other liminoids; Insecticidal effects are probable due to interference with several cellular processes; In animal experiments, causes neurotoxicity and reversible reproductive toxicity; Causes mild irritation and is a dermal sensitizer; In human case reports, encephalopathy develops within hours of ingesting 5-10 ml of neem seed oil; [Krieger, p. 147-54]

Exposure Assessment
Explanatory Notes

Flash point > 58 deg C; [HSDB]

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

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