Agent Name

Azaspiracid

CAS Number

214899-21-5

Formula

C47-H71-N-O12

Major Category

Biological Agents

Synonyms

Azaspiracid-1; [ChemIDplus]

Category

Seafood Toxins

Description

Colorless solid; [HSDB]

Sources/Uses

A toxin from the microalgae of the genus Protoperidinium; Found in contaminated mussels (Mytilus edulis) caught off the coast of Ireland; Causes multiple organ damage; Used in cancer research; [HSDB]

Comments

Causes small intestinal bleeding and other changes to the liver in multiple-dose toxicity testing of mice; [RTECS] Causes symptoms typical of diarrheic shellfish poisoning (diarrhea, vomiting, and abdominal pain), but the toxin is azaspiracid, not okadaic acid or dinophysistoxins; [PMID 18728760] Diarrheic shellfish poisoning is caused by marine dinoflagellates; toxins include okadaic acid, dinophysistoxins, and azaspiracid. Symptoms begin within 30 minutes to 2 hours and include nausea, vomiting, and diarrhea. [Olson, p. 246-7]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

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Health Studies

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Toxicity Information

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Chemical Information

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Other Information

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