Agent Name


CAS Number




Major Category



3,4-Dihydro-4-oxo-3-benzotriazinylmethyl O,O-diethyl phosphorodithioate; 3-Diethoxyphosphinothioylthiomethyl-1,2,3-benzotriazin-4(3H)-one; 3-Diethyloxyphosphinothioylthiomethyl-1,2,3-benzotriazin-4(3H)-one; Athyl-gusathion; Azinfos-ethyl [Dutch]; Azinophos-ethyl; Azinos; Azinphos-aethyl [German]; Azinphos-ethyl; Azinphos-etile [Italian]; Azinugec E; BAY 16255; BAY 16259; Bayer 16259; Benzotriazine derivative of an ethyl dithiophosphate; Bionex; Cotnion-ethyl; Crysthion; ENT 22,014; Ethyl Gusathion; Ethyl azinphos; Ethyl guthion; Ethyl homolog of guthion; Gusathion; Gusathion A; Gusathion A-M; Gusathion H; Gusathion H and K; Gusathion K; Gusathion K forte; Gusation A; Gutex; Guthion (ethyl); O,O-Diaethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiophosphat [German]; O,O-Diaethyl-S-(4-oxobenzotriazin-3-methyl)-dithiophosphat [German]; O,O-Diethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) phosphorodithioate (9CI); O,O-Diethyl S-(4-oxobenzotriazino-3-methyl)phosphorodithioate; O,O-Diethyl S-(4-oxobenzyltriazine-3-methyl) dithiophosphate; O,O-Diethyl phosphorodithioate S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one; O,O-Diethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithio fosfaat [Dutch]; O,O-Diethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiofosfaat [Dutch]; O,O-Diethyl-S-(4-oxo-3H-1,2,3-benzotriazine-3-yl)-methyl-dithiophosphate; O,O-Dietil-S-((4-oxo-3H-1,2,3-benzotriazin-3-il)-metil)-ditiofosfato [Italian]; Phosphorodithioic acid, O,O-diethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) ester; Phosphorodithioic acid, O,O-diethyl ester, S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one; R 1513; S-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl) O,O-diethyl phosphorodithioate; S-3,4-Dihydro-4-oxobenzo(d)(1.2.3)triazin-3-ylmethyl O,O-diethyl phosphorodithioate; Sepizin L; Triazotion [Russian]; [ChemIDplus] UN2783


Organophosphate Insecticides


Colorless solid; [HSDB] Colorless crystalline solid; [MSDSonline]


Used as a non-systemic insecticide and acaricide to protect fruits, vegetables, cotton, tobacco, ornamentals, other crops, and forestry; [HSDB]


Effects in high dose animal studies include depression of cholinesterase activity; [HSDB] Extremely toxic cholinesterase inhibitor that may cause death as a result of minor exposure to small amounts; [CAMEO] Toxic by ingestion, skin absorption, or inhalation; [Reference #1] May cause irritation; Effects in high dose animal studies include convulsions; [MSDSonline] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]


No longer used or produced in the US or Canada (high toxicicity); [HSDB]

Reference Link

INCHEM PDS: Azinphos-ethyl - 1994

Exposure Assessment

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

2.4E-6 mm Hg

Lethal Concentration

LC50 (rat) = 390 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, solid, toxic."

Adverse Effects
Other Poison


Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information


Chemical Information

Search ChemIDplus

Related Information in HazMap

Occupational diseases associated with exposure to this agent:


Industrial Processes with risk of exposure: