Agent Name

Crufomate

CAS Number

299-86-5

Formula

C12-H19-Cl-N-O3-P

Major Category

Pesticides

Synonyms

2-Chloro-4-(1,1-dimethylethyl)phenyl methyl methylphosphoramidate; 4-Tert. butyl 2-chlorophenyl methylphosphoramidate de methyle [French]; 4-t-Butyl-2-chlorophenyl methyl methylphosphoramidate; 4-t-Butyl-2-chlorophenylmethyl methyl phosphoramidate; 4-tert-Butyl-2-chlorophenyl N-methyl O-methylphosphoramidate; 4-tert-Butyl-2-chlorophenyl O-methyl methylphosphoroamidate; 4-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate; 4-tert. Butyl 2-chlorophenyl methylphosphoramidate de methyle [French]; Amidofos; Amidophos; Crufomate A; Crufomate [ANSI]; Crufomato [INN-Spanish]; Crufomatum [INN-Latin]; Dowco 132; M-1261; Methylphosphoramidic acid 2-chloro-4-(1,1-dimethylethyl)phenyl methyl ester; Methylphosphoramidic acid, 4-t-butyl-2-chlorophenyl methyl ester; Montrel; N,O-Dimethyl-o-(4-tert-butyl-2-chlorophenyl)phosphoramidate; O-(4-Tert butyl-2-chloor-fenyl)-O-methyl-fosforzuur-N-methyl-amide [Dutch]; O-(4-Tert-butyl-2-chlor-phenyl)-O-methyl-phosphorsaeure-N-methylamid [German]; O-(4-Terz.-butil-2-cloro-fenil)-O-metil-fosforammide [Italian]; O-(4-tert Butyl-2-chloor-fenyl)-O-methyl-fosforzuur-N-methyl-amide [Dutch]; O-(4-tert-Butyl-2-chlor-phenyl)-O-methyl-phosphorsaeure-N-methylamid [German]; O-(4-tert-Butyl-2-chlorophenyl) O-methyl N-methylamido phosphate; O-Methyl O-2-chloro-4-tert-butylphenyl N-methylamidophosphate; O-Methyl-O-(4-tert-butyl-2-chlorophenyl)methylphosphoramidate; Phenol, 4-t-butyl-2-chloro-, ester with methyl methylphosphoramidate; Phosphoramidic acid, 4-tert-butyl-2-chlorophenylphosphoramidate; Phosphoramidic acid, methyl-, 2-chloro-4-(1,1-dimethylethyl)phenyl methyl ester; Phosphoramidic acid, methyl-, 4-tert-butyl-2-chlorophenyl methyl ester; Ruelene; Ruelene 25E; Ruelene drench; Rulene; [ChemIDplus]

Category

Organophosphate Insecticides

Description

White, crystalline solid in pure form. [pesticide] [Note: Commercial product is a yellow oil.]; [NIOSH]

Sources/Uses

Used to kill cattle lice, grubs, and horn flies; [HSDB]

Comments

A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC]

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

5 mg/m3

Vapor Pressure

3.75E-5 mm Hg

Lethal Concentration

LCLo (rat) = 12 mg/m3/4h

Adverse Effects
Other Poison

Organophosphate

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent:

Processes

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