Agent Name

Azocyclotin

CAS Number

41083-11-8

Formula

C20-H35-N3-Sn

Major Category

Metals

Synonyms

(1H-1,2,4-Triazolyl)tricyclohexylstannane; 1-(Tricyclohexylstannyl)-1H-1,2,4-triazole; BAY BUE 1452; Peropal; Tri(cyclohexyl)-1H-1,2,4-triazol-1-yltin; Tri(cyklohexyl)-1H-1,2,4-triazol-1-ylstannium [Czech]; Stannane, (1H-1,2,4-triazol-1-yl)tricyclohexyl-; [ChemIDplus] UN3146

Category

Tin Compounds, Organic

Description

Colorless solid; [HSDB]

Sources/Uses

Used as a long lasting acaricide on fruit (including citrus), vines, hops, cotton, vegetables, and ornamentals; Not registered for use in the US; [HSDB]

Comments

A strong skin and eye irritant, based on animal studies; [HSDB] A skin and respiratory tract irritant; May cause severe damage to eyes; [eChemPortal: ESIS] Rapidly hydrolyzed to cyhexatin and 1,2,4-triazole in aqueous solution; In high-dose animal studies, causes spastic gait, diarrhea, and apathy; Corrosive to rabbit skin; At doses >2 mg/kg/day causes miscellaneous adverse effects in animals, including elevated liver enzymes; Unlikely to be genotoxic; [Reference #1] See "Cyhexatin." See "1,2,4-Triazole."

Reference Link

INCHEM JMPR: Azocyclotin - 2005

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.1 mg/m3, as Sn

STEL (ACGIH)

0.2 mg/m3, as Sn

PEL (OSHA)

0.1 mg/m3, as Sn

MAK

0.1 mg/m3, inhalable fraction, as Sn

IDLH (NIOSH)

25 mg/m3, as Sn

Vapor Pressure

4.5E-13 mm Hg

Lethal Concentration

LC50 (rat) = 17 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organotin compound, solid, n.o.s." Organic tin compounds have a "skin" designation and are classified as "A4" (Not classifiable as human carcinogen); [ACGIH]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: