Agent Name

Cyanamide

CAS Number

420-04-2

Formula

C-H2-N2

Major Category

Nitrogen Compounds

Synonyms

Amidocyanogen; Carbimide; Carbodiimide; Cyanogen nitride; Hydrogen cyanamide [Note: Cyanamide is also a synonym for Calcium cyanamide.] [NIOSH]

Category

Cyanamides

Description

Deliquescent, crystalline solid; [CHEMINFO]

Sources/Uses

Used in the organic synthesis of dicyandiamide in melamine manufacturing; also used in fumigants, metal cleaners, ore refining, and synthetic rubber production; [ACGIH]

Comments

The TLV basis for cyanamide is skin and eye irritation; May cause antabuse-like effect in exposed workers who ingest alcohol; [ACGIH] Allergic contact dermatitis has been reported. [Allergic contact dermatitis from cyanamide: report of 3 cases. Goday Bujan JJ, et al. Contact Dermatitis. 1994 Nov;31(5):331-2. No abstract available. Abstract in NIOSHTIC # 192164] Can cause liver injury after ingestion; [HSDB] Danger of skin sensitization; [MAK]

Reference Link

The adverse effects of hydrogen cyanamide on human health: an evaluation of inquiries to the New Zealand National Poisons Centre.

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

2 mg/m3

MAK

0.35 mg/m3(can also occur as vapor and aerosol)

Reference Link

ICSC: Cyanamide

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: