Agent Name


CAS Number




Major Category



Benzenesulfonamide, N-(2-mercaptoethyl)-, S-ester with O,O-diisopropylphosphorodithioate; Benzulfide; Betamec; Betasan; Betasan E; Betasan G; Betasan [OBSOLETE]; Disan; Disan (pesticide); Exporsan; Kayaphenone; N-(2-(O,O-Diisopropyldithiophosphoryl)ethyl)benzenesulfonamide; N-(2-Ethylthio)benzene sulphonamide-S,O,O-diisopropylphosphorodithioate; N-(2-Mercaptoethyl)benzenesulfonamide S-(O,O-diisopropyl phosphorodithioate); N-(2-Mercaptoethylbenzene)sulfonamide S-(O,O-diisopropylphosphorodithioate); N-(beta-O,O-Diisopropyldithiophosphorylethyl)benzenesulfonamide; O,O-Bis(1-methylethyl) S-(2-((phenylsulfonyl)amino)ethyl)phosphorodithioate (9CI); O,O-Bis(1-methylethyl)-S-(2-((phenylsulfonyl)amino)ethyl) phosphorodithioate; O,O-Di-isopropyl S-2-phenylsulphonylaminoethyl phosphorodithioate; O,O-Diisopropyl 2-(benzenesulfonamido)ethyl dithiophosphate; O,O-Diisopropyl S-(2-benzenesulfonylaminoethyl) phosphorodithioate; O,O-Diisopropyl dithiophosphate S-ester with N-(2-mercaptoethyl)benzenesulphonamide; O,O-Diisopropyl phosphorodithioate S-ester with N-(2-mercaptoethyl)benzenesulfonamide; Phosphorodithioic acid, O,O-bis(1-methylethyl) S-(2-((phenylsulfonyl)amino)ethyl) ester; Phosphorodithioic acid, O,O-diisopropyl ester, S-ester with N-(2-mercaptoethyl)benzenesulfonamide; Pre-San; Prefar; Prefar E; Prefer; R 4461; R-4461; S-(O,O-Diisopropyl phosphorodithioate) ester of N-(2-mercaptoethyl)benzenesulfonamide; S-(O,O-Diisopropylphosphorodithioate) of N-(2-mercaptoethyl)benzenesulfonamide; S-2-Benzenesulfonamidoethyl O,O-di-isopropyl phosphorodithioate; S-2-Benzenesulphonamidoethyl O,O-diisopropyl phosphorodithioate; S-beta-(Benzenesulfonamido)ethyl O,O-diisopropyl dithiophosphate; SAP; SAP (herbicide); [ChemIDplus]


Organophosphate Insecticides


Colorless to white solid; mp = 34 deg C; [ICSC] Colorless or amber liquid above 34.4 deg C; [HSDB] Amber liquid; mp = 33-36 deg C; Supercools and may remain liquid below these temperatures; [MSDSonline]


Used as a pre-emergence herbicide for control of annual grasses and broad-leaved weeds in lawns, turf, watermelons, cotton, rice, vegetables, rice, and other crops; [HSDB]


A cholinesterase inhibitor; [ICSC] Caused mild skin and eye irritation in rabbits; Effects observed in chronic feeding studies with rats include inhibition of cholinesterase activity and minor histopathological changes of liver; [HSDB] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

8.0E-7 mm Hg

Lethal Concentration

LC50 (rat) > 1,750 mg/m3/4h

Explanatory Notes

Flash point = 157 deg C; [HSDB]

Adverse Effects
Other Poison


Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information


Chemical Information

Search ChemIDplus

Related Information in HazMap

Occupational diseases associated with exposure to this agent:


Industrial Processes with risk of exposure: