Agent Name

Estragole

Alternative Name

1-Methoxy-4-(2-propenyl)benzene

CAS Number

140-67-0

Formula

C10-H12-O

Major Category

Biological Agents

Synonyms

1-Methoxy-4-(2-propenyl)benzene; 1-Allyl-4-methoxybenzene; 1-Methoxy-4-(2-propen-1-yl)benzene; 3-(p-Methoxyphenyl)propene; 4-Allyl-1-methoxybenzene; 4-Allylanisole; 4-Allylmethoxybenzene; 4-Methoxyallylbenzene; Allylphenyl methyl ether, p-; Anisole, p-allyl-; Benzene, 1-methoxy-4-(2-propenyl)-; Chavicol methyl ether; Chavicol, O-methyl-; Chavicyl methyl ether; Esdragol; Esdragole; Esdragon; Estragole (natural); Isoanethole; Methyl chavicol; Tarragon; Terragon; p-Allylanisole; p-Allylmethoxybenzene; p-Methoxyallylbenzene; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Colorless liquid with an odor of anise; [Hawley]

Sources/Uses

Naturally occurs in tarragon oil, basil oils, anise bark oil, and others; [Hawley] Used as a flavoring ingredient and a fragrance in perfumes and soaps; [HSDB]

Comments

Emergency treatment: "Essential oils"; Essential oils can cause CNS depression and aspiration pneumonia after ingestion; Commercial products of essential oils usually contain concentrations of 1% to 20%, and a potentially toxic exposure is 5-15 mL; No sensitization when tested at 3% in petrolatum on 25 volunteers; Minor liver damage found in rats fed 605 mg/kg/day for four days; [HSDB] Moderate irritant on rabbit skin; Causes somnolence and coma at lethal doses in rats; [RTECS];

Exposure Assessment
Vapor Pressure

0.05 mm Hg

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

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Health Studies

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Toxicity Information

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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent: