Agent Name

Benzethonium chloride

CAS Number




Major Category

Nitrogen Compounds


Diisobutyl phenoxy ethoxy ethyl dimethyl benzyl ammonium chloride; N,N-Dimethyl-N-(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)- ethyl)benzenemethanaminium chloride; (2-(2-(4-Diisobutylphenoxy)ethoxy)ethyl)dimethylbenzylammonium chloride; Ammonium, benzyldimethyl(2-(2-(p-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)-, chloride; Anti-germ 77; Antiseptol; Antiseptol (quarternary compound); BZT; BZT (VAN); Banagerm; Benzenemethanaminium, N,N-dimethyl-N-(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)-, chloride; Benzethoni chloridum; Benzethonii chloridum [INN-Latin]; Benzethonium chloride 1622; Benzethoniumchloride; Benzetonio cloruro; Benzetonio cloruro [DCIT]; Benzetonium chloride; Benzyldimethyl(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)ammonium chloride; Benzyldimethyl(2-(2-(p-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)ammonium chloride; Benzyldimethyl-p-(1,1,3,3-tetramethylbutyl)phenoxyethoxy-ethylammonium chloride; Chlorure de benzethonium [INN-French]; Cloruro de benzetonio [INN-Spanish]; Diapp; Diisobutylphenoxyethoxyethyl dimethyl benzyl ammonium chloride; Diisobutylphenoxyethoxyethyldimethyl benzyl ammonium chloride; Disilyn; Formula 144; Hyamine; Hyamine 1622; Inactisol; Kylacol; N,N-Dimethyl-N-(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)-benzenemethanaminium chloride; Phemeride; Phemerol chloride; Phemithyn; Polymine D; QAC; Quatrachlor; Sanizol; Solamin; Solamine; p-Diisobutyl phenoxyethoxyethyl dimethyl benzylammonium chloride; p-tert-Octylphenoxyethoxyethyldimethylbenzylammonium chloride; [ChemIDplus]


Quaternary Amines


Colorless or white solid in various forms; Hygroscopic; Soluble in water; [ICSC] White powder; [MSDSonline] Very bitter taste; 1% solution has a pH of 4.8-5.5; [HSDB]


Used as a cationic detergent, germicide for cleansing food and dairy utensils, swimming pool algaecide, dandruff-control agent, deodorant, topical antiseptic, spermicide, and astringent; [HSDB] Used as a preservative in cosmetics and pharmaceuticals and as a reagent for determining protein in cerebrospinal fluid; [Merck Index]


When used as a spermaticide, can cause vaginal irritation; Fatal dose by ingestion is 1-3 grams; In fatal cases after accidental ingestion, patients had vomiting, convulsions, and coma; Concentrations of 0.1% to 1% are eye irritants; Skin absorption is probably insignificant; [HSDB] Corrosive to eyes; A skin irritant; [ICSC] Allergic contact dermatitis is infrequently documented; [Marks, p. 266] Quaternary ammonium compounds have curare-like properties when concentrated solutions are ingested; Affected patients may have methemoglobinemia and hemolysis and die within 1-3 hours; Elevated liver function tests were reported; Concentrated solutions can cause burns; No data on carcinogenicity or teratogenicity; [IPCS-PIMs] No interference with embryo development in rats; No human data; [REPROTOX] An irritant; May cause serious eye injury; Effects in high-dose animal studies include convulsions; [MSDSonline] See "Benzalkonium chloride."

Exposure Assessment
Explanatory Notes

mp = 160-165 deg C; [Merck Index]

Adverse Effects

Other CNS Neurotoxin


Hepatotoxin, Secondary


Methemoglobinemia, Secondary


Skin Burns

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Toxicity Information


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