Agent Name

Cyclonite

Alternative Name

RDX

CAS Number

121-82-4

Formula

C3-H6-N6-O6

Major Category

Other Uses

Synonyms

Cyclotrimethylenetrinitramine; Hexahydro-1,3,5-trinitro-s-triazine; Trimethylenetrinitramine; 1,3,5-Trinitro-1,3,5-triazacyclohexane; RDX; [NIOSH] UN0391

Category

Explosives

Description

White, crystalline powder. [Note: A powerful high explosive.] [NIOSH]

Sources/Uses

Used as an explosive and rodenticide; [ACGIH]

Comments

In subchronic feeding studies of dogs (50 mg/kg/day for 6 weeks), one of seven dogs died, and the others had weight loss and seizures. Methemoglobinemia was not reported. Animals in chronic studies show liver injury. Workers have experienced central nervous system effects including seizures after occupational exposure. [ACGIH]

Restricted

Transportation forbidden for Cyclonite; Transportation forbidden by passenger aircraft/rail and cargo aircraft for Cyclonite (desensitized or wetted with >15% water; [HMT]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.5 mg/m3

Vapor Pressure

4.1E-9 mm Hg

Reference Link

ATSDR - ToxFAQs - RDX (Cyclonite)

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: