Agent Name

Benzothiazole

CAS Number

95-16-9

Formula

C7-H5-N-S

Major Category

Nitrogen Compounds

Synonyms

1-Thia-3-azaindene; Benzosulfonazole; O-2857; Vangard BT; [ChemIDplus]

Category

Thiazoles

Description

Yellow liquid with an unpleasant odor; mp = 2 deg C; [HSDB] Colorless liquid; [Alfa Aesar MSDS]

Sources/Uses

Used as a flavor, antimicrobial agent, and component of cyanine dyes; Derivatives used as rubber accelerators; [HSDB] Used in organic synthesis; [Merck Index]

Comments

Not irritating to skin, but irritating to eyes of rabbits; Lethal-dose gavage study of cats produced mild methemoglobinemia and Heinz bodies in up to 100% of erythrocytes; [IUCLID] Safe when used as a flavoring agent in food; [JECFA] A mild skin and eye irritant; Causes pulmonary emboli and other changes to liver in dermal lethal-dose study of rabbits and oral lethal-dose study of rats; [RTECS] A mild skin and strong eye irritant; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

0.01 mm Hg

Odor Threshold Low

0.08 ppm

Odor Threshold High

0.4 ppm

Lethal Concentration

LC (rat) > 1,400 mg/m3/6h

Explanatory Notes

Odor threshold from CHEMINFO;

Adverse Effects
Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Other Information

No other related information on this agent was found.