Agent Name

Demeton

Alternative Name

Systox

CAS Number

8065-48-3

Formula

C8-H19-O3-P-S2.C8-H19-O3-P-S2

Major Category

Pesticides

Synonyms

BAY 10756; Bayer 8169; Demox; Diethoxythiophosphoric acid ester of 2-ethylmercaptoethanol; E 1059; ENT 17,295; Ethyl systox; Mercaptofos; Mercaptophos; O,O-Diethyl 2-ethylmercaptoethyl thiophosphate; O,O-Diethyl O(and S)-2-(ethylthio)ethyl phosphorothioate mixture; Septox; Systemox; Systox; beta-Ethylmercaptoethyl diethyl thionophosphate; Phosphorothioic acid, O,O-diethyl O-(2-(ethylthio)ethyl) ester, mixt. With O,O-diethyl S-(2-(ethylthio)ethyl) phosphorothioate; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Amber, oily liquid with a sulfur-like odor. [insecticide]; [NIOSH] Colorless liqiud; [ICSC]

Sources/Uses

Used as an insecticide, especially on ornamentals and nursery stock; [HSDB]

Comments

Its toxicity and potency are similar to that of parathion. [ACGIH] A cholinesterase inhibitor that may cause cardiac disorders, convulsions, cyanosis, and respiratory failure; Can be absorbed through skin; [ICSC] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.05 mg/m3, inhalable fraction and vapor

PEL (OSHA)

0.1 mg/m3

IDLH (NIOSH)

10 mg/m3

Vapor Pressure

0.0003 mm Hg

Lethal Concentration

LCLo (cat) = 15 mg/m3/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: