Agent Name

Butylated hydroxytoluene

Alternative Name

2,6-Di-tert-butyl-p-cresol

CAS Number

128-37-0

Formula

C15-H24-O

Major Category

Other Uses

Synonyms

2,6-Di-tert-butyl-p-cresol; Ionol CP-antioxidant; 1-Hydroxy-4-methyl-2,6-di-tert-butylbenzene; 2,6-Bis(1,1-dimethylethyl)-4-methylphenol; 2,6-Di-t-butyl-4-methylphenol; 2,6-Di-t-butyl-p-cresol; 2,6-Di-terc.butyl-p-kresol [Czech]; 2,6-Di-tert-butyl-1-hydroxy-4-methylbenzene; 2,6-Di-tert-butyl-4-cresol; 2,6-Di-tert-butyl-4-hydroxytoluene; 2,6-Di-tert-butyl-4-methylhydroxybenzene; 2,6-Di-tert-butyl-4-methylphenol; 2,6-Di-tert-butyl-p-cresol; 2,6-Di-tert-butyl-p-methylphenol; 3,5-Di-tert-butyl-4-hydroxytoluene; 4-Hydroxy-3,5-di-tert-butyltoluene; 4-Methyl-2,6-di-terc. Butylfenol [Czech]; 4-Methyl-2,6-di-tert-butylphenol; 4-Methyl-2,6-tert-butylphenol; AO 29; AO 4; AO 4K; AOX 4; AOX 4K; Advastab 401; Agidol; Agidol 1; Alkofen BP; Antioxidant 264; Antioxidant 29; Antioxidant 30; Antioxidant 4; Antioxidant 4K; Antioxidant DBPC; Antioxidant KB; Antioxidant MPJ; Antioxidant T 501; Antox QT; Antrancine 8; BAT; BHT; BHT (food grade); BHT 264; BUKS; Butylated hydroxytoluene; Butylated hydroxytoluol; Butylhydroxytoluene; Butylohydroksytoluenu [Polish]; CAO 1; CAO 3; Catalin antioxydant 1; Catalin cao-3; Chemanox 11; DBPC; DBPC (technical grade); Dalpac; Deenax; Di-tert-butyl-p-cresol; Di-tert-butyl-p-cresol (VAN); Di-tert-butyl-p-methylphenol; Dibunol; Dibutylated hydroxytoluene; Impruvol; Ionol; Ionol (antioxidant); Ionol 1; Ionol CP; Ionole; Kerabit; Nocrac 200; Nonox TBC; P 21; P21; Parabar 441; Paranox 441; Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-; Stavox; Sumilizer BHT; Sustane; Sustane BHT; Swanox BHT; Tenamen 3; Tenamene 3; Tenox BHT; Tonarol; Topanol; Topanol O; Topanol OC; Toxolan P; Vanlube PC; Vanlube PCX; Vianol; Vulkanox KB; o-Di-tert-butyl-p-methylphenol; [ChemIDplus]

Category

Preservatives

Description

White to pale-yellow, crystalline solid with a slight, phenolic odor; (food preservative); [NIOSH]

Sources/Uses

Used as an anti-oxidant in gasoline, oils, waxes, rubbers, paints, and plastics; purified forms are used as anti-oxidants in foods; [ACGIH] Used as an "anti-skinning agent in paints and inks"; [Merck Index] BHT is a preservative and anti-oxidant used in food, cosmetics, and medications. Industrial applications include: animal feeds, jet fuels, rubber, plastics, paints, and glues. [Marks, p. 138-9]

Comments

Permitted in food at levels up to 200 ppm; Despite its widespread use, BHT is a rare skin sensitizer; Percent positive patch test responses were 0.1% in a US series in 1992-4; Contact urticaria has been reported; [Marks, p. 138-9] May have effects on the liver; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

2 mg/m3, inhalable fraction and vapor

MAK

10 mg/m3, inhalable fraction

Vapor Pressure

0.01 mm Hg

Explanatory Notes

Flash point = 260 deg F;

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: