Agent Name

o-Dianisidine

Alternative Name

3,3`-Dimethoxybenzidine

CAS Number

119-90-4

Formula

C14-H16-N2-O2

Major Category

Nitrogen Compounds

Synonyms

1,1'-Biphenyl)-4,4'-diamine, 3,3'-dimethoxy-; 3,3'-Dianisidine; 3,3'-Dimethoxy-4,4'-diaminobiphenyl; 3,3'-Dimethoxy-4,4'-diaminodiphenyl; 3,3'-Dimethoxybenzidin [Czech]; 3,3'-Dimethoxybenzidine; 3,3'-Dimethoxybiphenyl-4,4'-diamine; 3,3'-Dimetossibenzodina [Italian]; 4,4'-Bi-o-anisidine; 4,4'-Diamino-3,3'-dimethoxybiphenyl; 4,4'-Diamino-3,3'-dimethoxydiphenyl; Acetamine Diazo Black RD; Acetamine Diazo Navy RD; Amacel Developed Navy SD; Azoene Fast Blue Base; Azofix Blue B Salt; Azogene Fast Blue B; Azogene Fast Blue B Salt; Benzidene, 3,3'-dimethoxy-; Biphenyl, 4,4'diamino-3,3'dimethoxy; Blue BN Base; Blue Base NB; Blue Base irga B; Brentamine Fast Blue B Base; C.I. 24110; C.I. Azoic Diazo Component 48; C.I. Disperse Black 6; Cellitazol B; Cibacete Diazo Navy Blue 2B; Di-p-aminodi-m-methoxydiphenyl; Diacel Navy DC; Diacelliton Fast Grey G; Dianisidine; Diato Blue Base B; Diazo Fast Blue B; Disperse Black 6; Fast Blue B Base; Fast Blue Base B; Fast Blue DSC Base; Hiltonil Fast Blue B Base; Kayaku Blue B Base; Lake Blue B Base; Meisei Teryl Diazo Blue HR; Mitsui Blue B Base; Naphthanil Blue B Base; Neutrosel Navy BN; Setacyl Diazo Navy R; Spectrolene Blue B; o-Dianisidin [Czech, German]; o-Dianisidina [Italian]; o-Dianisidine; o-Dimethoxybenzidine; ortho-Dianisidine; [ChemIDplus]

Category

Amines, Polyaromatic

Description

Colorless crystals that turn a violet color on standing; Note: Used as a basis for many dyes; [NIOSH]

Sources/Uses

Used as a chemical intermediate in the production of dyes and dianisidine diisocyanate; Also used to dye leather, paper, plastics, rubber, and textiles; [HSDB]

Comments

Causes liver injury and tumors in experimental animals; [HSDB] No published epidemiology studies on dye workers and cancer; Currently, dye production in closed systems with low risk to workers; [NTP] Classified by NIOSH as a carcinogen--reduce exposure to lowest feasible concentration; [NIOSH] "Symptoms: Irritation skin"; [CAMEO]

Exposure Assessment
Explanatory Notes

Flash point = 206 deg C;

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: