Agent Name

o-Dianisidine

Alternative Name

3,3`-Dimethoxybenzidine

CAS Number

119-90-4

Formula

C14-H16-N2-O2

Major Category

Nitrogen Compounds

Synonyms

1,1'-Biphenyl)-4,4'-diamine, 3,3'-dimethoxy-; 3,3'-Dianisidine; 3,3'-Dimethoxy-4,4'-diaminobiphenyl; 3,3'-Dimethoxy-4,4'-diaminodiphenyl; 3,3'-Dimethoxybenzidin [Czech]; 3,3'-Dimethoxybenzidine; 3,3'-Dimethoxybiphenyl-4,4'-diamine; 3,3'-Dimetossibenzodina [Italian]; 4,4'-Bi-o-anisidine; 4,4'-Diamino-3,3'-dimethoxybiphenyl; 4,4'-Diamino-3,3'-dimethoxydiphenyl; Acetamine Diazo Black RD; Acetamine Diazo Navy RD; Amacel Developed Navy SD; Azoene Fast Blue Base; Azofix Blue B Salt; Azogene Fast Blue B; Azogene Fast Blue B Salt; Benzidene, 3,3'-dimethoxy-; Biphenyl, 4,4'diamino-3,3'dimethoxy; Blue BN Base; Blue Base NB; Blue Base irga B; Brentamine Fast Blue B Base; C.I. 24110; C.I. Azoic Diazo Component 48; C.I. Disperse Black 6; Cellitazol B; Cibacete Diazo Navy Blue 2B; Di-p-aminodi-m-methoxydiphenyl; Diacel Navy DC; Diacelliton Fast Grey G; Dianisidine; Diato Blue Base B; Diazo Fast Blue B; Disperse Black 6; Fast Blue B Base; Fast Blue Base B; Fast Blue DSC Base; Hiltonil Fast Blue B Base; Kayaku Blue B Base; Lake Blue B Base; Meisei Teryl Diazo Blue HR; Mitsui Blue B Base; Naphthanil Blue B Base; Neutrosel Navy BN; Setacyl Diazo Navy R; Spectrolene Blue B; o-Dianisidin [Czech, German]; o-Dianisidina [Italian]; o-Dianisidine; o-Dimethoxybenzidine; ortho-Dianisidine; [ChemIDplus]

Category

Amines, Polyaromatic

Description

Colorless crystals that turn a violet color on standing; Note: Used as a basis for many dyes; [NIOSH]

Sources/Uses

Used as a chemical intermediate in the production of dyes and dianisidine diisocyanate; Also used to dye leather, paper, plastics, rubber, and textiles; [HSDB]

Comments

Causes liver injury and tumors in experimental animals; [HSDB] No published epidemiology studies on dye workers and cancer; Currently, dye production in closed systems with low risk to workers; [NTP] Classified by NIOSH as a carcinogen--reduce exposure to lowest feasible concentration; [NIOSH] "Symptoms: Irritation skin"; [CAMEO]

Exposure Assessment
Explanatory Notes

Flash point = 206 deg C;

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: