| Agent Name | 2-N-Dibutylaminoethanol |
|---|---|
| CAS Number | 102-81-8 |
| Formula | C10-H23-N-O |
| Major Category | Nitrogen Compounds |
| Synonyms | 2-Di-n-butylaminoethanol; 2-Dibutylaminoethanol; 2-N-Dibutylaminoethanol; BU2AE; Di(n-butyl)ethanolamine; Dibutylaminoethanol; Dibutylethanolamine; N,N-(Dibutylamino)ethanol; N,N-Dibutyl-2-hydroxyethylamine; N,N-Dibutyl-N-(2-hydroxyethyl)amine; N,N-Dibutylethanolamine; beta-N-Dibutylaminoethyl alcohol; beta-n-Dibutylaminoethyl alcohol; [ChemIDplus] UN2873 |
| Category | Ethanolamines |
| Description | Colorless liquid with a faint, amine-like odor; [NIOSH] |
| Sources/Uses | Used as a curing agent for polyurethane foams and silicone resins; a conditioner for cellulose acetate filaments; a corrosion inhibitor in lubricants and hydraulic fluids; and in the synthesis of other organic compounds; [ACGIH] |
| Comments | In animals: irritation of eyes, skin, and nose; corneal necrosis; weight loss; [NIOSH] Molten substance may cause severe burns; [CAMEO] May be corrosive to skin and eyes based on animal results; [CHEMINFO] DBAE is an irritant of the nose and ieys. Animal studies show that DBAE inhibits acetylcholinesterase. The median lethal dose in rats dying of respiratory arrest is 89.1 mg/kg. Five rats with inhalation exposures of 33 ppm 6 hours a day for 5 days had no mortality. [ACGIH] |
| Exposure Assessment | |
| BEI | Cholinesterase activity in red blood cells = 70% of individual's baseline, sample time discretionary |
| Skin Designation (ACGIH) | Yes |
| TLV (ACGIH) | 0.5 ppm |
| Vapor Pressure | 0.1 mm Hg |
| Explanatory Notes | Flash point = 210 deg F; |
| Flammability (NFPA) | |
| Adverse Effects | |
| Dermatotoxin | Skin Burns |
| Links to Other NLM Databases | |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
2-N-Dibutylaminoethanol
CAS Number
102-81-8
Formula
C10-H23-N-O
Major Category
Nitrogen Compounds
Synonyms
2-Di-n-butylaminoethanol; 2-Dibutylaminoethanol; 2-N-Dibutylaminoethanol; BU2AE; Di(n-butyl)ethanolamine; Dibutylaminoethanol; Dibutylethanolamine; N,N-(Dibutylamino)ethanol; N,N-Dibutyl-2-hydroxyethylamine; N,N-Dibutyl-N-(2-hydroxyethyl)amine; N,N-Dibutylethanolamine; beta-N-Dibutylaminoethyl alcohol; beta-n-Dibutylaminoethyl alcohol; [ChemIDplus] UN2873
Category
Ethanolamines
Description
Colorless liquid with a faint, amine-like odor; [NIOSH]
Sources/Uses
Used as a curing agent for polyurethane foams and silicone resins; a conditioner for cellulose acetate filaments; a corrosion inhibitor in lubricants and hydraulic fluids; and in the synthesis of other organic compounds; [ACGIH]
Comments
In animals: irritation of eyes, skin, and nose; corneal necrosis; weight loss; [NIOSH] Molten substance may cause severe burns; [CAMEO] May be corrosive to skin and eyes based on animal results; [CHEMINFO] DBAE is an irritant of the nose and ieys. Animal studies show that DBAE inhibits acetylcholinesterase. The median lethal dose in rats dying of respiratory arrest is 89.1 mg/kg. Five rats with inhalation exposures of 33 ppm 6 hours a day for 5 days had no mortality. [ACGIH]
Exposure Assessment
BEI
Cholinesterase activity in red blood cells = 70% of individual's baseline, sample time discretionary
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.5 ppm
Vapor Pressure
0.1 mm Hg
Explanatory Notes
Flash point = 210 deg F;
Flammability (NFPA)
Adverse Effects
Dermatotoxin
Skin Burns
Links to Other NLM Databases
Toxicity Information
Chemical Information
Related Information in HazMap
Processes
Industrial Processes with risk of exposure: