Agent Name

Dibutyl phosphate

CAS Number

107-66-4

Formula

C8-H19-O4-P

Major Category

Other Classes

Synonyms

DP 4 (coupling agent); Di-n-butyl hydrogen phosphate; Di-n-butyl phosphate; Dibutyl acid phosphate; Dibutyl hydrogen phosphate; Dibutyl phosphate; Phosphoric acid, dibutyl ester; [ChemIDplus]

Category

Organophosphates, Other

Description

Pale-amber, odorless liquid; [NIOSH]

Sources/Uses

Used as an a catalyst and an antifoaming agent; [ACGIH] Used as a catalyst for resins and paints, a dielectric medium, a plasticizer (added to polymers to effect flexibility and/or toughness), a hydraulic fluid, and an antistatic in the textile industry"; [HSDB]

Comments

Workers reported respiratory irritation and headache. [ACGIH] A skin, eye, and respiratory tract irritant; [ICSC] Liver changes were found in animals fed fatal doses of 1000 mg/kg. [HSDB]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

5 mg/m3, inhalable fraction and vapor

PEL (OSHA)

5 mg/m3

IDLH (NIOSH)

30 mg/m3

Excerpts from Documentation for IDLHs

Basis for revised IDLH: Due to the lack of relevant acute toxicity data, the revised IDLH for dibutyl phosphate is 30 ppm based on an analogy to tributyl phosphate which has a revised IDLH of 30 ppm.

Vapor Pressure

9.6E-5 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: