Agent Name

Bromophos

CAS Number

2104-96-3

Formula

C8-H8-Br-Cl2-O3-P-S

Major Category

Pesticides

Synonyms

4-Bromo-2,5-dichlorophenyl dimethyl phosphorothionate; Brofene; Bromo-phos-methyl; Bromofos; Bromofos-methyl; Bromofosum [INN-Latin]; Bromovur; Brophene; Bruomophos [Russian]; Cela S 1942; Cx99; Drillzid; EL 400; ENT 27,162; Metabrom; Mexion; Monsanto CP 51969; Netal; Nexagan; Nexion; Nexion 40; Nexion 5G; Nexion LC40; O,O-Dimethyl O-(2,5-dichloro-4-bromophenyl) phosphorothioate; O,O-Dimethyl O-(2,5-dichloro-4-bromophenyl) thiophosphate; O,O-Dimethyl O-(4-bromo-2,5-dichlorophenyl) phosphorothioate; O,O-Dimethyl-O-(2,5-dichlor-4-bromphenyl)-thionophosphat [German]; O,O-Dimethyl-O-(2,5-dichloro-4-bromophenyl)phosphorothioate; O,O-Dimethyl-O-2,5-dichloro-4-bromophenyl phosphorothionate; O-(4-Brom-2,5-dichlor-phenyl)-O,O-dimethyl-monothiophosphat [German]; O-(4-Bromo-2,5-dichlorophenyl) O,O-dimethyl monothiophosphate; O-(4-Bromo-2,5-dichlorophenyl) O,O-dimethyl phosphorothioate; O-(4-Bromo-2,5-dicloro-fenil)-O,O-dimetil-monotiofosfato [Italian]; O-(4-Broom-2,5-dichloor-fenyl)-O,O-dimethyl-monothiofosfaat [Dutch]; OMS 658; OMS-658; Omexan; Phenol, 4-bromo-2,5-dichloro-, O-ester with O,O-dimethyl phosphorothioate; Phosphorothioic acid O-(4-bromo-2,5-dichlorophenyl) O,O-dimethyl ester; S 1942; S-1942; Sovinexion; Thiophosphate de O,O-dimethyle et de O-4-bromo-2,5-dichlorophenyle [French; [ChemIDplus] UN2783

Category

Organophosphate Insecticides

Description

Yellow solid; [Merck Index] Colorless solid; [MSDSonline]

Sources/Uses

Used as an insecticide and acaricide for fruit, vegetables, field crops, ornamentals, forestry, stored products, public health (i.e. flies and mosquitoes), household use, animal houses, and animal dips; [HSDB]

Comments

Depressed plasma cholinesterase was the only clinical effect found in applicators in a village in Africa; Shown to inhibit cholinesterase activity in high-dose feeding and dermal animal studies; Effects in a 100 day high-dose feeding study with rats include slow growth rates and minor degenerative damage to kidneys and liver; [HSDB] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

No longer registered as a pesticide for use in the US; [HSDB]

Reference Link

INCHEM PDS: Bromophos - 1994

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

0.00013 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticides, solid, toxic."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: