Agent Name

Bromoxynil octanoate

CAS Number

1689-99-2

Formula

C15-H17-Br2-N-O2

Major Category

Pesticides

Synonyms

2,6-Dibromo-4-cyanophenyl octanoate; 3,5-Dibromo-4-hydroxybenzonitrile octanoate; 3,5-Dibromo-4-octanoyloxy-benzonitrile; 4-Cyano-2,6-dibromophenyl octanoate; Brominal W; Bromoxynil octanoic acid ester; M&B 10731; NPH 1320; Octanoic acid ester of 3,5-dibromo-4-hydroxybenzonitrile; RP-16272; Benzonitrile, 3,5-dibromo-4-octanoyloxy-; Octanoic acid, 2,6-dibromo-4-cyanophenyl ester; [ChemIDplus]

Category

Herbicides, Other

Description

Solid; [Merck Index] Nearly white crystalline solid; [MSDSonline]

Sources/Uses

Used as herbicide for cereals, field corn, popcorn, other crops, and alfalfa in Conservation Reserve Program; [HSDB]

Comments

A mild skin and eye irritant; May cause skin sensitization; Effects in a 13 week feeding study with rats include decrease in body weight (not associated with decrease in food intake), increased kidney and liver weights, hematological changes, and myocardial degeneration and necrosis; "Four workers in a manufacturing plant making both bromoxynil and ioxynil developed typical symptoms of uncoupler poisoning including excessive perspiration, thirst, fever, emesis, myalgia, and weight loss. ... The effects reversed rapidly after exposure ceased." [HSDB] May cause skin sensitization; [eChemPortal: ESIS] May cause irritation; May cause skin sensitization; [MSDSonline] See "Bromoxynil."

Exposure Assessment
PEL (OSHA)

5 mg/m3, as CN

MAK

2 mg/m3, inhalable fraction, as CN

Vapor Pressure

4.8E-6 mm Hg

Lethal Concentration

LC50 (rat) = 720 mg/m3;

Reference Link

eChemPortal: IUCLID Dataset: Bromoxynil octanoate - 2000

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Uncoupler

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: