Agent Name

Butylparaben

CAS Number

94-26-8

Formula

C11-H14-O3

Major Category

Other Uses

Synonyms

Butyl parahydroxybenzoate; 4-(Butoxycarbonyl)phenol; 4-Hydroxybenzoic acid butyl ester; Aseptoform butyl; Benzoic acid, 4-hydroxy-, butyl ester; Benzoic acid, p-hydroxy-, butyl ester; Butoben; Butyl 4-hydroxybenzoate; Butyl butex; Butyl chemosept; Butyl p-hydroxybenzoate; Butyl paraben; Butyl parasept; Butyl tegosept; Butyl-Parasept; Nipabutyl; Preserval B; SPF; Solbrol B; Tegosept B; Tegosept butyl; n-Butyl hydroxybenzoate; n-Butyl p-hydroxybenzoate; n-Butyl parahydroxybenzoate; p-Hydroxybenzoic acid butyl ester; [ChemIDplus]

Category

Preservatives

Description

Colorless solid; Insoluble in water (207 mg/L at 20 deg C); Very hygroscopic; [HSDB] White odorless solid; Insoluble in water; [CAMEO] Powder; Slightly soluble in water; [MSDSonline]

Sources/Uses

Used as an antifungal agent, preservative in antiseptic creams, food preservative, and pharyngeal antiseptic; [HSDB] The parabens (methyl, ethyl, propyl, and butyl) were the most widely used preservatives in cosmetics (0.1% to 0.8%) until their sensitizing potential was recognized; [Marks, p. 115]

Comments

Parabens are an uncommon cause of allergic contact dermatitis; [Marks, p. 115] A skin irritant; Causes liver injury in feeding studies of mice; [HSDB] A skin and eye irritant; A potential skin sensitizer; [CAMEO] An eye and mild skin irritant; May cause skin sensitization; [eChemPortal: ERMA] "Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin." [Kanerva, p. 1822-3]

Restricted

Cancelled-- no longer contained in any registered pesticide products for use in the US; [HSDB]

Exposure Assessment
Vapor Pressure

0.000186 mm Hg

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: