Agent Name

Hexachlorobutadiene

CAS Number

87-68-3

Formula

C4-Cl6

Major Category

Other Classes

Synonyms

1,1,2,3,4,4-Hexachloro-1,3-butadiene; 1,3-Butadiene, 1,1,2,3,4,4-hexachloro-; 1,3-Butadiene, hexachloro-; 1,3-Hexachlorobutadiene; C 46; C-46; Dolen-pur; GP-40-66:120; HCBD; Hexachlor-1,3-butadien [Czech]; Hexachlorobutadiene; Perchlorobutadiene; [ChemIDplus] UN2279

Category

Halogenated Aliphatics, Unsaturated

Description

Clear, colorless liquid with a mild, turpentine-like odor; [NIOSH]

Sources/Uses

Used as a solvent, heat transfer liquid in transformers, and hydraulic fluid; produced as a byproduct of hydrocarbon chlorination processes; [ACGIH] Used as a fumigant in parts of Europe against Phylloxera on grapes; [HSDB]

Comments

Kidney injury reported in chronic feeding and inhalation studies of experimental animals; [ACGIH] Liquid is corrosive. Vapor causes skin, eye, and respiratory tract irritation. May cause kidney injury; [ICSC] Irritating to skin; Toxic by ingestion, inhalation, or skin absorption; [MSDSonline]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.02 ppm

MAK

0.02 ppm

Vapor Pressure

0.2 mm Hg

Odor Threshold Low

1.1 ppm

Lethal Concentration

LC50 (mouse) = 370 mg/m3

Explanatory Notes

Flash point = 90 deg C; Odor threshold from CHEMINFO;

Reference Link

ATSDR - ToxFAQs - Hexachlorobutadiene

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Nephrotoxin

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: