Agent Name

Cadmium (2+) NTA

CAS Number

49784-44-3

Formula

C6-H6-Cd-N-O6.H

Major Category

Metals

Synonyms

Cadmium nitrilotriacetate; Hydrogen (N,N-bis(carboxymethyl)glycinato(3-)-N,O,O',O'')cadmate; [ChemIDplus]

Category

Organic Acids, Metal Salts

Comments

"There is inadequate evidence in humans for the carcinogenicity of nitrilotriacetic acid and its salts." [IARC] NTA complexes of mercury, cadmium, and nickel degrade more slowly than complexes of lead, zinc, and iron; Undegraded NTA may accumulate in the environment; [HSDB] See "Cadmium" and the linked occupational diseases.

Exposure Assessment
BEI

Cd in urine = 5 ug/g creatinine; Cd in blood = 5 ug/L; sampling time not critical; "Monitoring in blood should be preferred during the initial year of exposure and whenever changes in the degree of exposure are suspected." [ACGIH]

Bioaccumulates

Yes

TLV (ACGIH)

0.01 mg/m3, as Cd ( 0.002 mg/m3, as Cd, respirable fraction)

PEL (OSHA)

0.005 mg/m3, as Cd, see 29 CFR 1910.1027

IDLH (NIOSH)

9 mg/m3, as Cd

Adverse Effects
Nephrotoxin

Yes

Reproductive Toxin

Yes

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: