Agent Name

Caffeic acid

CAS Number

331-39-5

Formula

C9-H8-O4

Major Category

Other Classes

Synonyms

3,4-Dihydroxybenzeneacrylic acid; 3,4-Dihydroxycinnamic acid; 3-(3,4-Dihydroxy phenyl)-2-propenoic acid; 3-(3,4-Dihydroxyphenyl)-2-propenoic acid; 3-(3,4-Dihydroxyphenyl)propenoic acid; 4-(2'-Carboxyvinyl)-1,2-dihydroxybenzene; 4-(2-Carboxyethenyl)-1,2-dihydroxybenzene; Cinnamic acid, 3,4-dihydroxy-; [ChemIDplus]

Category

Organic Acids

Description

Yellow solid; Slightly soluble in cold water, soluble in hot water; [Merck Index] Light yellow powder; [MSDSonline]

Sources/Uses

A constituent of plants; Can be isolated form green or roasted coffee; [Merck Index] No known significance as commercial product; [HSDB] "Caffeic acid is found in many fruits, vegetables, seasonings and beverages consumed by humans, principally in conjugated forms such as chlorogenic acid." [IARC]

Comments

Causes epithelial hyperplasia in forestomach of rats given 20 g/kg of diet for 4 weeks; [HSDB] An irritant; Targets G.I. tract and kidneys; [MSDSonline]

Exposure Assessment
Vapor Pressure

2.52E-7 mm Hg

Adverse Effects
IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Other Information

No other related information on this agent was found.