Agent Name

Carfentrazone-ethyl

CAS Number

128639-02-1

Formula

C15-H14-Cl2-F3-N3-O3

Major Category

Pesticides

Synonyms

Aim; Aurora; Aurora (pesticide); Aurora 50WG; F 8426; F8426; Kuaimieling; Spotlight; Spotlight 24EC; Benzenepropanoic acid, .alpha.,2-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)-4-fluoro-, ethyl ester; Ethyl 2-chloro-3-(2-chloro-4-fluoro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)propanoate; [ChemIDplus] Quicksilver; [ACGIH]

Category

Herbicides, Protox-Inhibiting

Description

Yellow liquid; [Merck Index] Yellow-orange liquid with a mild odor of petroleum; [HSDB] Viscous yellow-orange liquid; [ACGIH]

Sources/Uses

Used as post-emergence herbicide for control of broadleaf weeds, winter annuals, and mustards in cereals, corn, cotton, and rice; Also used as cotton defoliant; [HSDB] Also used on turf and ornamentals; [ACGIH]

Comments

The lowest NOAEL of 3 mg/kg was found in female rats from a 2-year chronic study and this number is used as the basis for the recommended limit. Higher doses produce both liver damage and increased urinary porphyrin excretion. No human data available; [ACGIH] The protox inhibitor herbicides (Fomesafen, Oxadiazon, Lactofen, Sulfentrazone, Carfentrazone-ethyl, Oxyfluorofen and Bifenox) can disrupt porphyrin metabolism; "It has been speculated that a transient form of porphyria variegate may occur following a massive exposure or long-term exposure to lower doses." [HSDB] May cause irritation; [MSDSonline] See "Fluthiacet-methyl."

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
TLV (ACGIH)

1 mg/m3, inhalable particulate matter

Vapor Pressure

1.2E-7 mm Hg

Lethal Concentration

LC50 (rat) >5,090 mg/m3;

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Processes

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