Agent Name

Chloracetic anhydride

CAS Number

541-88-8

Formula

C4-H4-Cl2-O3

Major Category

Other Classes

Synonyms

2-Chloroacetic anhydride; Acetic acid, chloro-, anhydride; Chloroacetic acid anhydride; Chloroacetic anhydride; Chloroacetyl anhydride; Chloroethanoic anhydride; Monochloroacetic acid anhydride; Sym-dichloroacetic anhydride; alpha,alpha'-Dichloroacetic anhydride; [ChemIDplus] UN3261

Category

Acid Anhydrides, Other

Description

Colorless to slightly yellow solid with a pungent odor; [HSDB] White or off-white crystalline powder; [MSDSonline]

Sources/Uses

Used in the N-acetylation of amino acids and to make cellulose chloroacetates; [Merck Index] No evidence of commercial production in the US; [HSDB]

Comments

A skin and eye irritant; Emergency treatment: "irritants"; [HSDB] Reacts with water evolving hydrochloric acid; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Causes lacrimation and may cause edema and chemical pneumonitis after inhalation; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.03 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Corrosive solid, acidic, organic, n.o.s."

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.