Agent Name

Chlorobutanol

Alternative Name

Chloretone

CAS Number

57-15-8

Formula

C4-H7-Cl3-O

Major Category

Other Classes

Synonyms

Chloretone; 1,1,1-Trichloro-2-methyl-2-propanol; 1,1,1-Trichloro-tert-butyl alcohol; 2-(Trichloromethyl)-2-propanol; 2-Propanol, 1,1,1-trichloro-2-methyl-; 2-Propanol, 2-methyl-1,1,1-trichloro-; Acetochlorone; Acetonchloroform; Acetone chloroform; Anhydrous chlorobutanol; Chlorbutanol; Chlorbutanolum; Chlorbutol; Chlorbutolum; Chloreton; Chlorobutanol, anhydrous; Chlorobutanolum [INN-Latin]; Chlortran; Clorobutanol [INN-Spanish]; Clorobutanolo; Clorobutanolo [DCIT]; Clortran; Coliquifilm; Dentalone; HCP; Khloreton; Methaform; Sedaform; Trichlorisobutylalcohol; Trichloro-t-butyl alcohol; Trichloro-tert-butanol; beta,beta,beta-Trichloro-tert-butyl alcohol; [ChemIDplus]

Category

Halogenated Alcohols

Description

Colorless to white solid; [Merck Index] Crystalline solid; [MSDSonline]

Sources/Uses

Used as a plasticizer for cellulose esters and ethers, in medical practice (preservative, antimicrobial agent, anesthetic in dentistry, sedative and hypnotic, antiemetic), and in veterinary practice (antiseptic, local anesthetic, sedative, antiemetic, antipruritic, and hypnotic); [HSDB]

Comments

A skin and eye irritant; 0.4% solution caused keratitis in rabbit eyes following continuous bathing; Emergency treatment is for "chloral hydrate and related agents." [HSDB]

Exposure Assessment
Vapor Pressure

0.83 mm Hg

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: