Agent Name | o-Tolidine |
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Alternative Name | 3,3'-Dimethylbenzidine |
CAS Number | 119-93-7 |
Formula | C14-H16-N2 |
Major Category | Nitrogen Compounds |
Synonyms | 3,3'-Dimethylbenzidine; 2-Tolidin [German]; 2-Tolidina [Italian]; 2-Tolidine; 3,3'-Dimethyl-(1,1'-biphenyl)-4,4'-diamine; 3,3'-Dimethyl-4,4'-biphenyldiamine; 3,3'-Dimethyl-4,4'-diaminobiphenyl; 3,3'-Dimethyl-4,4'-diphenyldiamine; 3,3'-Dimethylbenzidine; 3,3'-Tolidine; 4,4'-Bi-o-toluidine; 4,4'-Di-o-toluidine; 4,4'-Diamino-3,3'-dimethylbiphenyl; 4,4'-Diamino-3,3'-dimethyldiphenyl; Bianisidine; C.I. 37230; C.I. Azoic Diazo Component 113; CI 37230; CI Azoic diazo component 113; Diaminoditolyl; Diaminotolyl; Fast Dark Blue Base R; Orthotolidine; o-Tolidine; [ChemIDplus] |
Category | Benzidine and Derivatives |
Description | White to reddish crystals or powder. [Note: Darkens on exposure to air. Often used in paste or wet cake form. Used as a basis for many dyes.]; [NIOSH] |
Sources/Uses | Used as an intermediate in the production of dyes and pigments; used as a curing agent for polyurethane elastomers, coatings, and rigid foams; [HSDB] |
Comments | A carcinogen in experimental animals; [HSDB] In subchronic feeding studies, animals develop liver and kidney damage and bone marrow depression. [ACGIH] |
Exposure Assessment | |
Skin Designation (ACGIH) | Yes |
Vapor Pressure | 6.92E-7 mm Hg |
Explanatory Notes | Carcinogen--No TLV; NIOSH recommends 60 minute ceiling of 0.02 mg/m3; Flash point = 137 deg C; |
Adverse Effects | |
Hepatotoxin | Hepatotoxin, Secondary |
IARC Carcinogen | Possible Carcinogen |
NTP Carcinogen | Anticipated Human Carcinogen |
ACGIH Carcinogen | Confirmed Animal |
Links to Other NLM Databases | |
Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
Toxicity Information | |
Chemical Information | |
Biomedical References | |
Related Information in HazMap | |
Processes | Industrial Processes with risk of exposure: |