| Agent Name | o-Tolidine |
|---|---|
| Alternative Name | 3,3'-Dimethylbenzidine |
| CAS Number | 119-93-7 |
| Formula | C14-H16-N2 |
| Major Category | Nitrogen Compounds |
| Synonyms | 3,3'-Dimethylbenzidine; 2-Tolidin [German]; 2-Tolidina [Italian]; 2-Tolidine; 3,3'-Dimethyl-(1,1'-biphenyl)-4,4'-diamine; 3,3'-Dimethyl-4,4'-biphenyldiamine; 3,3'-Dimethyl-4,4'-diaminobiphenyl; 3,3'-Dimethyl-4,4'-diphenyldiamine; 3,3'-Dimethylbenzidine; 3,3'-Tolidine; 4,4'-Bi-o-toluidine; 4,4'-Di-o-toluidine; 4,4'-Diamino-3,3'-dimethylbiphenyl; 4,4'-Diamino-3,3'-dimethyldiphenyl; Bianisidine; C.I. 37230; C.I. Azoic Diazo Component 113; CI 37230; CI Azoic diazo component 113; Diaminoditolyl; Diaminotolyl; Fast Dark Blue Base R; Orthotolidine; o-Tolidine; [ChemIDplus] |
| Category | Benzidine and Derivatives |
| Description | White to reddish crystals or powder. [Note: Darkens on exposure to air. Often used in paste or wet cake form. Used as a basis for many dyes.]; [NIOSH] |
| Sources/Uses | Used as an intermediate in the production of dyes and pigments; used as a curing agent for polyurethane elastomers, coatings, and rigid foams; [HSDB] |
| Comments | A carcinogen in experimental animals; [HSDB] In subchronic feeding studies, animals develop liver and kidney damage and bone marrow depression. [ACGIH] |
| Exposure Assessment | |
| Skin Designation (ACGIH) | Yes |
| Vapor Pressure | 6.92E-7 mm Hg |
| Explanatory Notes | Carcinogen--No TLV; NIOSH recommends 60 minute ceiling of 0.02 mg/m3; Flash point = 137 deg C; |
| Adverse Effects | |
| Hepatotoxin | Hepatotoxin, Secondary |
| IARC Carcinogen | Possible Carcinogen |
| NTP Carcinogen | Anticipated Human Carcinogen |
| ACGIH Carcinogen | Confirmed Animal |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Biomedical References | |
| Related Information in HazMap | |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
o-Tolidine
Alternative Name
3,3'-Dimethylbenzidine
CAS Number
119-93-7
Formula
C14-H16-N2
Major Category
Nitrogen Compounds
Synonyms
3,3'-Dimethylbenzidine; 2-Tolidin [German]; 2-Tolidina [Italian]; 2-Tolidine; 3,3'-Dimethyl-(1,1'-biphenyl)-4,4'-diamine; 3,3'-Dimethyl-4,4'-biphenyldiamine; 3,3'-Dimethyl-4,4'-diaminobiphenyl; 3,3'-Dimethyl-4,4'-diphenyldiamine; 3,3'-Dimethylbenzidine; 3,3'-Tolidine; 4,4'-Bi-o-toluidine; 4,4'-Di-o-toluidine; 4,4'-Diamino-3,3'-dimethylbiphenyl; 4,4'-Diamino-3,3'-dimethyldiphenyl; Bianisidine; C.I. 37230; C.I. Azoic Diazo Component 113; CI 37230; CI Azoic diazo component 113; Diaminoditolyl; Diaminotolyl; Fast Dark Blue Base R; Orthotolidine; o-Tolidine; [ChemIDplus]
Category
Benzidine and Derivatives
Description
White to reddish crystals or powder. [Note: Darkens on exposure to air. Often used in paste or wet cake form. Used as a basis for many dyes.]; [NIOSH]
Sources/Uses
Used as an intermediate in the production of dyes and pigments; used as a curing agent for polyurethane elastomers, coatings, and rigid foams; [HSDB]
Comments
A carcinogen in experimental animals; [HSDB] In subchronic feeding studies, animals develop liver and kidney damage and bone marrow depression. [ACGIH]
Exposure Assessment
Skin Designation (ACGIH)
Yes
Vapor Pressure
6.92E-7 mm Hg
Explanatory Notes
Carcinogen--No TLV; NIOSH recommends 60 minute ceiling of 0.02 mg/m3; Flash point = 137 deg C;
Adverse Effects
Hepatotoxin
Hepatotoxin, Secondary
IARC Carcinogen
Possible Carcinogen
NTP Carcinogen
Anticipated Human Carcinogen
ACGIH Carcinogen
Confirmed Animal
Links to Other NLM Databases
Toxicity Information
Chemical Information
Biomedical References
Related Information in HazMap