Agent Name

o-Tolidine

Alternative Name

3,3'-Dimethylbenzidine

CAS Number

119-93-7

Formula

C14-H16-N2

Major Category

Nitrogen Compounds

Synonyms

3,3'-Dimethylbenzidine; 2-Tolidin [German]; 2-Tolidina [Italian]; 2-Tolidine; 3,3'-Dimethyl-(1,1'-biphenyl)-4,4'-diamine; 3,3'-Dimethyl-4,4'-biphenyldiamine; 3,3'-Dimethyl-4,4'-diaminobiphenyl; 3,3'-Dimethyl-4,4'-diphenyldiamine; 3,3'-Dimethylbenzidine; 3,3'-Tolidine; 4,4'-Bi-o-toluidine; 4,4'-Di-o-toluidine; 4,4'-Diamino-3,3'-dimethylbiphenyl; 4,4'-Diamino-3,3'-dimethyldiphenyl; Bianisidine; C.I. 37230; C.I. Azoic Diazo Component 113; CI 37230; CI Azoic diazo component 113; Diaminoditolyl; Diaminotolyl; Fast Dark Blue Base R; Orthotolidine; o-Tolidine; [ChemIDplus]

Category

Benzidine and Derivatives

Description

White to reddish crystals or powder. [Note: Darkens on exposure to air. Often used in paste or wet cake form. Used as a basis for many dyes.]; [NIOSH]

Sources/Uses

Used as an intermediate in the production of dyes and pigments; used as a curing agent for polyurethane elastomers, coatings, and rigid foams; [HSDB]

Comments

A carcinogen in experimental animals; [HSDB] In subchronic feeding studies, animals develop liver and kidney damage and bone marrow depression. [ACGIH]

Exposure Assessment
Skin Designation (ACGIH)

Yes

Vapor Pressure

6.92E-7 mm Hg

Explanatory Notes

Carcinogen--No TLV; NIOSH recommends 60 minute ceiling of 0.02 mg/m3; Flash point = 137 deg C;

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: