Agent Name

Diethylthiophosphoryl chloride

Alternative Name

O,O-Diethyl chlorothiophosphonate

CAS Number

2524-04-1

Formula

C4-H10-Cl-O2-P-S

Major Category

Other Classes

Synonyms

O,O-Diethyl chlorothiophosphonate; Diethoxythiophosphoryl chloride; Diethyl chlorothiophosphate; Diethyl phosphorochloridothioate; Diethyl phosphorochloridothionate; Diethyl phosphorochlorothioate; Diethyl phosphorothiochloridate; Diethyl phosphorothionochloridate; Diethyl thiophosphoric chloride; Diethyl thiophosphoryl chloride; Diethylchlorothiophosphate; Diethylchlorthiofosfat [Czech]; Diethylthiophosphoric acid chloride; Ethyl PCT; O,O-Diethyl chloridophosphorothioate; O,O-Diethyl chloridothionophosphate; O,O-Diethyl chlorothionophosphate; O,O-Diethyl chlorothiophosphate; O,O-Diethyl phosphorochloridothioate; O,O-Diethyl phosphorochlorothioate; O,O-Diethyl phosphorothiochloridate; O,O-Diethyl phosphorothionochloridate; O,O-Diethyl thionophosphoric acid ester chloride; O,O-Diethyl thionophosphoric chloride; O,O-Diethyl thionophosphorochloridate; O,O-Diethyl thionophosphoryl chloride; O,O-Diethyl thiophosphoryl chloride; O,O-Diethylester kyseliny chlorthiofosforecne [Czech]; O,O-Diethylphosphorochloridothioate; O,O-Diethylthiophosphorochloridate; Phosphonothioic acid, chloro-, O,O-diethyl ester; Phosphorochloridothioic acid, O,O-diethyl ester; [ChemIDplus] UN2751

Category

Organophosphates, Other

Description

Colorless to light-amber liquid; [Hawley] Unpleasant odor; [CAMEO]

Sources/Uses

Used as intermediate for organophosphate pesticides, as an oil and gasoline additive, and in flame retardants and flotation agents; [HSDB]

Comments

A cholinesterase inhibitor; An eye and lung irritant; [Hawley] Decomposed by water evolving hydrogen chloride; May be absorbed through skin; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation can cause pulmonary edema; A cholinesterase inhibitor with possible cumulative effect; [ICSC] Emergency treatment: Acids; [HSDB] Corrosive to skin and eyes of rabbits; Effects observed in repeated dose inhalation studies with rodents include emphysema, alveolar thickening, collapse in areas of the lungs, kidney degeneration (tubular cortex), and cholinesterase inhibition; [IUCLID]

Exposure Assessment
Lethal Concentration

LC50 (rat) = 20 ppm/4h

Adverse Effects
Toxic Pneumonitis

Yes

Other Poison

Organophosphate

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Processes

Industrial Processes with risk of exposure: