Agent Name

Chlorthiophos

CAS Number

21923-23-9

Formula

C11-H15-Cl2-O3-P-S2

Major Category

Pesticides

Synonyms

CELA S-2957; CM S 2957; Celamerck S-2957; Celathion; Chlorthiophos I; ENT 27635; O-(2,5-Dichloro-4-(methylthio)phenyl) O,O-diethyl phosphorothioate; O-(Dichloro(methylthio)phenyl) O,O-diethyl phosphorothioate (3 isomers); OMS 1342; Phosphorothioic acid, O-(2,5-dichloro-4-(methylthio)phenyl) O,O-diethyl ester; S 2957; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Brown liquid; [HSDB] Yellow-brown liquid; Tendency to crystallize below 25 deg C; [CAMEO]

Sources/Uses

Used as insecticide and acaricide; [HSDB]

Comments

A cholinesterase inhibitor; May be absorbed through skin; [CAMEO] Effects in high-dose animal studies include convulsions, dyspnea, and inhibition of cholinesterase; [RTECS] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

2.4E-6 mm Hg

Adverse Effects
Other Poison

Organophosphate

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