Agent Name

Crotoxyphos

Alternative Name

Ciodrin

CAS Number

7700-17-6

Formula

C14-H19-O6-P

Major Category

Pesticides

Synonyms

Ciodrin; 1-Methylbenzyl-3-(dimethoxyphosphinyloxo)isocrotonate; 1-Phenylethyl (E)-3-((dimethoxyphosphinyl)oxy)-2-butenoate; 1-Phenylethyl 3-(dimethoxyphosphinoyloxy)isocrotonate; 1-Phenylethyl 3-(dimethoxyphosphinyloxy)isocrotonate; 2-Butenoic acid, 3-((dimethoxyphosphinyl)oxy)-, 1-phenylethyl ester, (E)-; 3-((Dimethoxyphosphinyl)oxy)-2-butenoic acid 1-phenylethyl ester; 3-Hydroxycrotonic acid alpha-methylbenzyl ester dimethyl phosphate; A-Methyl benzyl-3-hydroxy cis crotonate dimethyl phosphate; Crotonic acid, 3-hydroxy-, alpha-methylbenzyl ester, dimethyl phosphate, (E)- Crotoxyfos; Cyodrin; Decrotox Dimethylphosphate ester of alpha-methylbenzyl-3-hydroxy-cis-crotonate; Dimethyl (E)-1-methyl-2-(1-phenylethoxycarbonyl)vinyl phosphate; Dimethyl 2-(alpha-methylbenzyloxycarbonyl)-1-methylvinyl phosphate; Dimethyl phosphate of alpha-methylbenzyl 3-hydroxy-cis-crotonate; Dimethyl-cis-1-methyl-2-(1-phenylethoxycarbonyl)vinyl phosphate; Duo-Kill; Duravos; ENT 24,717; Kemdrin; O,O-Dimethyl O-(1-methyl-2-(1-phenylcarbethoxy)vinyl) phosphate; O,O-Dimethyl O-(1-methyl-2-carboxy-alpha-phenylethyl)vinyl phosphate; OMS 239; Pantozol 1; SD 4294; Shell SD 4294; Simax; Volfazol; alpha-Methyl benzyl-3-(dimethoxy-phosphinyloxy)-cis-crotonate; alpha-Methylbenzyl (E)-3-hydroxycrotonate ester with dimethyl phosphate; alpha-Methylbenzyl 3-hydroxy-cis-crotonate dimethyl phosphate ester; alpha-Methylbenzyl 3-hydroxycrotonate dimethyl phosphate; alpha-Methylbenzyl 3-hydroxycrotonate dimethylphosphate; cis-2-(1-Phenylethoxy)carbonyl-1-methylvinyl dimethylphosphate; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Pale straw-colored liquid; [Merck Index]

Sources/Uses

Used as insecticide to protect livestock (external use); [Merck Index]

Comments

A cholinesterase inhibitor; [Merck Index] No adverse effects to growth or histopathological changes were observed in 90 day feeding study with rats (males at 900 mg/kg diet and females 300 mg/kg diet); Cholinesterase inhibitor; [HSDB] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

1.4E-5 mm Hg

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: