Agent Name

Dichlorodifluoromethane

Alternative Name

Refrigerant 12

CAS Number

75-71-8

Formula

C-Cl2-F2

Major Category

Solvents

Synonyms

Refrigerant 12; Algofrene type 2; Arcton 12; Arcton 6; CFC 12; Chlorofluorocarbon 12; Dichlorodifluoromethane; Diclorodifluometano [Spanish]; Difluorodichloromethane; Dwuchlorodwufluorometan [Polish]; Dymel 12; Electro-CF 12; Eskimon 12; F 12; F 12; FC 12; FCC 12; FKW 12; Fluorocarbon-12; Forane 12; Freon 12; Freon F-12; Frigen 12; Genetron 12; Halon; Halon 122; Isceon 122; Isotron 12; Isotron 2; Kaiser chemicals 12; Ledon 12; Methane, dichlorodifluoro-; Propellant 12; R 12 (refrigerant); Refrigerant 12; Refrigerant R 12; Ucon 12; Ucon 12/halocarbon 12; [ChemIDplus] UN1028; UN1078

Category

Chlorofluorocarbons

Description

Colorless gas with an ether-like odor at extremely high concentrations; Note: Shipped as a liquefied compressed gas; [NIOSH]

Sources/Uses

Has been used as a refrigerant, propellant, and blowing agent; [ACGIH] Used in photography (film cleaner); [www.ci.tucson.az.us/arthazards/medium.html]

Comments

Possible frostbite from contact with liquid; [NIOSH] Dichlorodifluoromethane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] Release in confined space may result in suffocation; May cause CNS depression and cardiac arryhthmias; [ICSC]

Restricted

The manufacture of products containing CFC-12 propellants was banned by the EPA in 1978. [ACGIH]

Reference Link

Volatile Substance Abuse

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

1000 ppm

PEL (OSHA)

1000 ppm

MAK

1000 ppm

IDLH (NIOSH)

15000 ppm

Excerpts from Documentation for IDLHs

Exposure up to 60,000 ppm was tolerated for 80 minutes by 1 volunteer [NRC 1984]; when exposed at 40,000 ppm for 14 minutes and then at 20,000 ppm for 66 minutes, another volunteer developed EEG changes and had slurred speech and decreased psychologic test scores [NRC 1984].

Lethal Concentration

LC50 (guinea pigs) = 800,000ppm/30 min

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Other Poison

Simple Asphyxiant

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: