Agent Name

1,1-Dichloro-1-nitroethane

CAS Number

594-72-9

Formula

C2-H3-Cl2-N-O2

Major Category

Nitrogen Compounds

Synonyms

1,1-Dichloor-1-nitroethaan [Dutch]; 1,1-Dichlor-1-nitroaethan [German]; 1,1-Dichloro-1-nitroethane; 1,1-Dicloro-1-nitroetano [Italian]; Dichloro-1-nitroethane; Dichloronitroethane; Ethane, 1,1-dichloro-1-nitro-; Ethide; [ChemIDplus] UN2650

Category

Nitros, Aliphatic

Description

Colorless liquid with an unpleasant odor; [NIOSH]

Sources/Uses

Used in the synthesis of fumigants, insecticides, and rubber cements; [ACGIH]

Comments

Inhalation studies of animals show lung edema, congestion, and hemorrhage. The heart, blood vessels, liver, and kidneys are also damaged. [ACGIH] A lachrymator; [CHEMINFO]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

2 ppm

PEL (OSHA)

Ceiling(OSHA) = 10 ppm

IDLH (NIOSH)

25 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the study by Machle et al. [1945] in which autopsies on animals exposed to over 170 ppm for over 30 minutes revealed pulmonary edema and hemorrhage, with damage to the heart, liver, and kidneys. . . . Other animal data: Animals have tolerated 25 ppm for 204 hours [ Machle et al. 1945]. Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

16.9 mm Hg

Lethal Concentration

LCLo (guinea pigs) = 580 mg/m3/6H

Explanatory Notes

Flash point = 76 deg C;

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.