Agent Name

Coniine

CAS Number

458-88-8

Formula

C8-H17-N

Major Category

Biological Agents

Synonyms

(+)-Coniine; (S)-(+)-Coniine; (S)-2-Propylpiperidine; (S)-Coniine; (S)-beta-Propylpiperidine; Cicutin; Cicutine; Conicine; Coniin; Koniin; Piperidine, 2-propyl-, (S)-; d-Conicine; [ChemIDplus]

Category

Plant Toxins

Description

Colorless liquid; Darkens and polymerizes upon exposure to light and air; [Merck Index]

Sources/Uses

Principle toxin of poison hemlock; [Merck Index]

Comments

Coniine from the poison hemlock (Conium maculatum) is a nicotine-like alkaloid that causes vomiting, pallor, and diaphoresis that usually resolves within 1-2 hours. In severe cases, patients have seizures and respiratory arrest. [Olson, p. 341, 299] Oral LD50 (mouse) = 100 mg/kg; [RTECS]

Exposure Assessment
Vapor Pressure

0.69 mm Hg

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.