Agent Name

Coumachlor

CAS Number

81-82-3

Formula

C19-H15-Cl-O4

Major Category

Pesticides

Synonyms

3-((alpha-Acetonyl)-4-chlorbenzyl)-4-hydroxycumarin [IUPAC]; 3-(1-(4-Chloorfenyl)-3-oxo-butyl)-4-hydroxy-cumarine [Dutch]; 3-(1-(4-Chlor-phenyl)-3-oxo-butyl)-4-hydroxy-cumarin [German]; 3-(1-(4-Chlorophenyl)-3-oxo-butyl)-4-hydroxy-coumarine [French]; 3-(1-(4-Chlorophenyl)-3-oxobutyl)-4-hydroxy-2H-1-benzopyran-2-one; 3-(1-(4-Chlorophenyl)-3-oxobutyl)-4-hydroxy-2H-1-benzopyran-2-one (9CI); 3-(1-(4-Chlorophenyl)-3-oxobutyl)-4-hydroxycoumarin; 3-(1-(4-Cloro-fenil)-3-oxo-butil)-4-idrossicumarina [Italian]; 3-(1-Acetyl-2-(p-chlorophenyl)ethyl)-4-hydroxycoumarin; 3-(alpha-(p-Chlorphenyl)-beta-acetylaethyl)-4-hydroxycumarin [German]; 3-(alpha-Acetonyl-4-chlorobenzyl)-4-hydroxycoumarin; 3-(alpha-Acetonyl-p-chlorobenzyl)-4-hydroxycoumarin; 3-(alpha-p-Chlorophenyl-beta-acetylethyl)-4-hydroxycoumarin; 4-Hydroxy-3-(1-(4-chlorophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one; Coumachlore [ISO-French]; Cumachloor [Dutch]; Cumachlor [German]; Experimental Rodenticide 332; G-23133; Geigy Rodenticide Exp. 332; Kumachlor [Czech]; Ratilan; Tomorin; [ChemIDplus] UN3027

Category

Rodenticides, Anticoagulant

Description

Colorless solid; [HSDB]

Sources/Uses

Used as anticoagulant rodenticide (structural analog of warfarin); [Merck Index]

Comments

A vitamin K antagonist; In human poisoning cases after ingestion, causes disruption of clotting factors (lower doses) and hemorrhages (higher doses); [HSDB] First generation anticoagulant rodenticide; Discontinued by Ciba-Geigy in 1984; [INCHEM] See "Warfarin."

Restricted

No longer registered as a pesticide for use in the US; [HSDB]

Exposure Assessment
Vapor Pressure

7.17E-13 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Coumarin derivative pesticide, solid, toxic."

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Processes

Industrial Processes with risk of exposure: