Agent Name

Coumatetralyl

CAS Number

5836-29-3

Formula

C19-H16-O3

Major Category

Pesticides

Synonyms

2H-1-Benzopyran-2-one, 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-; 3-(1,2,3,4-Tetrahydro-1-naphthyl)-4-hydroxycumarin [German]; 3-(1,2,3,4-Tetrahydro-1-naphtyl)-4-hydroxycoumarine [French]; 3-(alpha-Tetral)-4-oxycoumarin; 3-(alpha-Tetralyl)-4-hydroxycoumarin; 3-(d-Tetralyl)-4-hydroxycoumarin; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naftyl)-cumarine [Dutch]; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-2H-1-benzopyran-2-one (8CI)(9CI); 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-cumarin; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin; 4-Idrossi-3-(1,2,3,4-tetraidro-1-naftil)-cumarina [Italian]; BAY 25634; BAY ENE 11183 B; Bayer 25 634; Coumarin, 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-; Cumatetralyl [German, Dutch]; ENE 11183 B; Endox; Endrocid; Endrocide; Racumin; Raucumin 57; Rodentin; [ChemIDplus] UN3027

Category

Rodenticides, Anticoagulant

Description

Yellowish-white odorless solid; Colorless when pure; [CAMEO] Colorless powder; [MSDSonline]

Sources/Uses

Used as anticoagulant rodenticide; Not currently produced or used in the US; [HSDB]

Comments

A vitamin K antagonist--causes clotting factor disruption and bleeding; Absorbed through skin; [HSDB] First generation anticoagulant rodenticide; [INCHEM] Registered for use in the EU; Not irritating to skin or eyes of rabbits; Not sensitizing to skin of guinea pigs; No evidence of mutagenic effects; No evidence of teratogenicity in rats or rabbits (although all anti-vitamin K rodenticides classified by this commission May cause harm to the unborn child based on the known human developmental toxicity of Warfarin); The commercial product Racumin Paste showed potential for skin sensitization in a Magnusson and Kligman study; [eChemPortal: ESIS] See "Warfarin."

Restricted

Not registered as a pesticide for use in the US; [HSDB]

Exposure Assessment
Vapor Pressure

6.38E-11 mm Hg

Lethal Concentration

LC50 (rat) = 39 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Coumarin derivative pesticide, solid, toxic."

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Processes

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