Agent Name

Diethyl phthalate

CAS Number

84-66-2

Formula

C12-H14-O4

Major Category

Plastics & Rubber

Synonyms

1,2-Benzenedicarboxylic acid, diethyl ester; Anozol; DEP; DPX-F5384; Di-n-ethyl phthalate; Diethyl 1,2-benzenedicarboxylate; Diethyl o-phenylenediacetate; Diethyl o-phthalate; Diethyl phthalate; Diethylester kyseliny ftalove [Czech]; Estol 1550; Ethyl phthalate; Neantine; Palatinol A; Phthalol; Phthalsaeurediaethylester [German]; Placidol E; Solvanol; Unimoll DA; o-Benzenedicarboxylic acid diethyl ester; o-Bis(ethoxycarbonyl)benzene; [ChemIDplus] UN8027

Category

Phthalate Esters

Description

Colorless to water-white, oily liquid with a very slight, aromatic odor. (pesticide); [NIOSH]

Sources/Uses

Plasticizer (added to polymers to effect flexibility and/or toughness); also used as an insect repellant and solvent; [ACGIH] Used as a solvent in cellulose acetate, fragrances, and cosmetics; [Merck Index #7371]

Comments

The heated compound is an irritant to the eyes and respiratory tract; [ACGIH] Allergic contact dermatitis reported; [Kanerva, p. 1782] In high-dose reproductive studies of rats and mice, DEHP and other phthalates cause testicular damage to males and increased fetal losses and malformations to pregnant females. [Frazier, p. 350-2] Low toxicity both acute and chronic, but could cause CNS depression if large dose absorbed; [HSDB]

Reference Link

Contact dermatitis from spectacle frames and hearing aid containing diethyl phthalate (No abstract available)

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

5 mg/m3

Vapor Pressure

0.002 mm Hg

Explanatory Notes

Flash point = 161 deg C;

Reference Link

ICSC: Diethyl phthalate

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Reproductive Toxin

Yes

Skin Sensitizer

Yes

ACGIH Carcinogen

Not Classifiable

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