Agent Name

Cycasin

CAS Number

14901-08-7

Formula

C8-H16-N2-O7

Major Category

Biological Agents

Synonyms

(Methyl-ONN-azoxy)-methyl-beta-D-glucopyranoside; (Methyl-ONN-azoxy)methyl beta-D-glucopyranoside; Cycas revoluta glucoside; Cykazine; Methylazoxymethanol glucoside; Methylazoxymethanol-beta-D-glucoside; Methylazoxymethanolbeta-D-glucoside; Methylazoxymethyl-b-D-glucopyranoside; beta-D-Glucopyranoside, (methyl-ONN-azoxy)methyl; [ChemIDplus]

Category

Plant Toxins

Description

Colorless solid; [HSDB]

Sources/Uses

Toxin derived from seeds of Cycus revoluta and other plants; [Merck Index] No commercial use in the US; Has been used as a food by Aboriginal groups in northern Australia; Soaking plant in water before consumption reduces its toxicity; The metabolite methylazoxymethanol, a biological methylating agent, is the active carcinogen; [HSDB]

Comments

Carcinogenic in mice, rats, hamsters, guinea pigs, rabbits, and fish producing malignant tumors mainly of the liver, kidney, and intestine; [IARC]

Adverse Effects
IARC Carcinogen

Possible Carcinogen

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Health Studies

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Toxicity Information

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Chemical Information

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