Agent Name

Cyclamic acid

CAS Number

100-88-9

Formula

C6-H13-N-O3-S

Major Category

Other Uses

Synonyms

Cyclamate; Cyclamsaeure; Cyclohexanesulfamic acid; Cyclohexanesulphamic acid; Cyclohexylamidosulfuric acid; Cyclohexylamidosulphuric acid; Cyclohexylaminesulfonic acid; Cyclohexylaminesulphonic acid; Cyclohexylsulfamic acid; Cyclohexylsulphamic acid; Hexamic acid; N-(Cyclohexyl)aminosulfonsaeure; N-Cyclohexylsulfamic acid; N-Cyclohexylsulfamsaeure; N-Cyclohexylsulphamic acid; Polycat 200; Sucaryl; Sucaryl acid; Sulfamic acid, cyclohexyl-; Sulfuric acid monoamide, N-cyclohexyl-; [ChemIDplus]

Category

Food Additives

Description

White odorless solid; [Hawley] Fine white crystals; [MSDSonline]

Sources/Uses

Used as intermediate for its salts (non-caloric sweeteners); Used formerly as non-nutritive sweetener; [HSDB] Used as acidulant; [Hawley]

Comments

In lethal dose studies, mice have seizures; Oral LD50 (mouse) = 680 mg/kg; Oral LD50 (rat) = 12,000 mg/kg; [ChemIDplus] No toxic effects found in rats fed high doses for entire life; [HSDB] An irritant; May cause skin sensitization; Effects in lethal-dose animal studies include convulsions and injury to liver and kidneys; [MSDSonline] See "Potassium cyclamate." See "Sodium cyclamate."

Exposure Assessment
Vapor Pressure

2.7E-6 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

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