Agent Name

Cyclopentanone

CAS Number

120-92-3

Formula

C5-H8-O

Major Category

Solvents

Synonyms

Adipic ketone; Adipin keton; Dumasin; Ketocyclopentane; Ketopentamethylene; [ChemIDplus] UN2245

Category

Ketones (<C12)

Description

Water-white liquid with distinctive odor like peppermint; [Hawley] Colorless clear liquid; Polymerizes easily in presence of acids; [ICSC]

Sources/Uses

Used as intermediate for pharmaceuticals, biologicals, insecticides, and rubber chemicals; [Hawley]

Comments

A skin and eye irritant; A possible respiratory tract irritant; Can be absorbed through skin; [ICSC] Inhalation of high concentrations can cause CNS depression; [HSDB] May cause irritation or burns to skin and eyes; [CAMEO] A skin and eye irritant; [eChemPortal: ESIS] Oral LD50 (mouse) = 1820 mg/kg; Effects in high-dose animal studies include somnolence, coma, and other changes to liver; [RTECS] Safe when used as a flavoring agent; [JECFA]

Exposure Assessment
Vapor Pressure

11.4 mm Hg

Lethal Concentration

LC50 (rat) = 19,500 mg/m3

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: