Agent Name

Cytochalasin E

CAS Number

36011-19-5

Formula

C28-H33-N-O7

Major Category

Biological Agents

Synonyms

21,23-Dioxa(13)cytochalasa-13,19-diene-1,17,22-trione, 6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E)-; 6,7-Epoxy-10-phenyl-5,6,16,18-tetramethyl-21,23-dioxa-(13)cytochalas-13,19-diene-17,22-dione; CYTOCHALASIN E; [ChemIDplus]

Category

Mycotoxins

Description

Solid; [HSDB] White solid; [MSDSonline]

Sources/Uses

Cytochalasins are a group of mold metabolites having various effects on animal cells; More than twenty cytochalasins have been isolated from different mold species; Used in cytological research and in studying the polymerization properties of actin; Most studied is cytochalasin B; [Merck Index]

Comments

Causes ataxia, cyanosis, and coma at lethal doses in rats; [RTECS] Cause inhibitory effects on cell processes; No reports of chronic effects or carcinogenicity in humans; [HSDB] See "Cytochalasin B."

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