Agent Name

Dehydroacetic acid

CAS Number

520-45-6

Formula

C8-H8-O4

Major Category

Other Classes

Synonyms

2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-; 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione, ion(1-),; 2-Acetyl-5-hydroxy-3-oxo-4-hexenoic acid, delta-lactone; 2H-Pyran-2-one, 3-acetyl-4-hydroxy-6-methyl-; 3-Acetyl-6-methylpyran-2,4(3H)-dione; 3-Acetyl-4-hydroxy-6-methyl-2H-pyran-2-one; 3-Acetyl-6-methyl-2,4-pyrandione; 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione; 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione. Enol form; 3-Acetyl-6-methyldihydropyrandione-2,4; 4-Hexenoic acid, 2-acetyl-5-hydroxy-3-oxo-, delta-lactone; Acetic acid, dehydro-; Biocide 470F; DHA (VAN); DHAA; DHS; Dehydracetic acid; Kyselina dehydroacetova [Czech]; Methylacetopyronone; [ChemIDplus]

Category

Organic Acids

Description

Colorless odorless solid; Highly reactive; [Hawley] White to cream-colored solid; [Merck Index] White odorless powder; [MSDSonline]

Sources/Uses

Used as a plasticizer, bactericide, preservative, and fungicide; Also used in toothpastes and pickles; [HSDB]

Comments

Monkeys had seizures in feeding studies (TDLo =3300 mg/kg/18D-I); [RTECS] Rats fed 0.3 gm/kg over 34 days had weight loss; No ill effects in rats fed 0.1 gm/kg for over 2 years; [HSDB] An irritant; [MSDSonline]

Exposure Assessment
Explanatory Notes

VP = 1.9 mm Hg at 100 deg C; [HSDB]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: