Agent Name

Dehydroheliotridine

CAS Number

26400-24-8

Formula

C8-H11-N-O2

Major Category

Nitrogen Compounds

Synonyms

(+)-Dehydroheliotridine; 3,8-Dehydroheliotridine; 1H-Pyrrolizine-7-methanol, 2,3-dihydro-1-hydroxy-, (S)-; Heliotridine, 3,8-didehydro- (8CI); [ChemIDplus]

Category

Pyrroles

Sources/Uses

The major unbound metabolite of lasiocarpine and heliotrine (pyrrolizidine alkaloids found in the plant Heliotropium europaeum); [HSDB]

Comments

Growth retardation and teratogenic effects observed in embryos of rats administered 30-90 mg/kg by IP injection on day 14 of pregnancy and effects on embryo observed at day 20; Higher doses nearly stopped growth in many tissues; [HSDB] See "Heliotridine."

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.