Agent Name

Dinobuton

Alternative Name

Dessin

CAS Number

973-21-7

Formula

C14-H18-N2-O7

Major Category

Pesticides

Synonyms

Dessin; (2-sek.Butyl-4,6-dinitrofenyl)-isopropylkarbonat [Czech]; 1-Methylethyl 2-(1-methylpropyl)-4,6-dinitrophenyl carbonate; 2,4-Dinitro-6-sec-butylphenyl isopropyl carbonate; 2,4-Dinitro-6-sek.butyl-isopropylphenylcarbonat [German]; 2-(1-Methyl-2-propyl)-4,6-dinitrophenyl isopropylcarbonate; 2-sec-Butyl-4,6-dinitrophenyl isopropyl carbonate; Acrex; Akrex; Carbonic acid, 1-methylethyl 2-(1-methylpropyl)-4,6-dinitrophenyl ester; Carbonic acid, 2-sec-butyl-4,6-dinitrophenyl isopropyl ester; DS 18302; Dinitro-sec-butylphenyl isopropyl carbonate; Dinofen; Drawinol; ENT 27,244; Isophen (pesticide); Isopropyl 2,4-dinitro-6-sec-butylphenyl carbonate; Isopropyl-2-(1-methyl-n-propyl)-4,6-dinitrophenyl carbonate; Kasebon; MC 1053; OMS 1056; Phenol, 2-sec-butyl-4,6-dinitro-, isopropylcarbonate; Sytasol; Talan; UC 19786; Union Carbide 19786; [ChemIDplus] UN2779

Category

Other Insecticides

Description

Pale yellow solid; [HSDB] Yellowish crystalline solid; [MSDSonline]

Sources/Uses

Used as non-systemic acaricide, fungicide, and miticide; [HSDB]

Comments

A metabolic stimulant that causes weight loss in high-dose animal studies; NOAEL for dogs is 4.5 mg/kg daily; [HSDB] One of the nitrocresolic compounds that can cause fatal poisonings after dermal contamination; Effects include uncoupling oxidative phosphorylation, acute hyperthermia, liver and kidney injury, and yellow staining of skin; [EPA Pesticides, p. 104-5] May cause irritation, GI disturbances, and cyanosis; May cause injury to cardiovascular system, kidneys, and liver; [MSDSonline] See "Dinocap."

Exposure Assessment
Vapor Pressure

1.1E-6 mm Hg

Lethal Concentration

LC50 (rat) = 80 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Substituted nitrophenol pesticide, solid, toxic."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Other Poison

Uncoupler

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: