Agent Name

Diallyl disulfide

CAS Number

2179-57-9

Formula

C6-H10-S2

Major Category

Other Classes

Synonyms

2-Propenyl disulfide; 2-Propenyl disulphide; 4,5-Dithia-1,7-octadiene; Allyl disulfide; Allyl disulphide; Di(2-propenyl) disulfide; Diallyl disulphide; Disulfide, di-2-propenyl; [ChemIDplus] UN1993

Category

Sulfur Compounds

Description

Liquid with a garlic odor; [HSDB] Colorless liquid with a garlic-like stench; [Alfa Aesar MSDS]

Sources/Uses

Major constituent of garlic oil; [ChemIDplus] Used as synthetic flavoring ingredient; [HSDB] Constitutes 86.9% of diallyl disulfides (DADs) which is 90% active ingredient of biopesticide used to control white rot (fungal pathogen) in onions, garlic, and leeks; DADs are volatile sulfur compounds found in garlic, onions, and other members of Allium species; [EPA]

Comments

One of the volatiles in onions responsible for lacrimation; Emergency treatment: Irritants; [HSDB] One of the major allergens in garlic and onions; [Kanerva, p. 1777] Diallyl disulfides (DADs): A moderate eye and strong skin irritant in rabbits; A skin sensitizer in guinea pigs using the Buehler method; Causes breathing abnormalities, wobbly gait, and decreased activity in oral lethal-dose studies of rats; Oral LD50 (rat) = 346 mg/kg; Dermal LD50 (rat) = 1,967 mg/kg; [EPA] Safe when used as a flavoring agent in food; [JECFA] A moderate skin and severe eye irritant; Causes hemolysis in oral lethal-dose study of rats; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

1 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Flammable liquid, n.o.s."

Adverse Effects
Skin Sensitizer

Yes

Lacrimator

Yes

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